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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL496356
Molecular formula	C27H34ClN5O3
IUPAC name	[1-[1-[4-(4-chloroanilino)-6,7-dimethoxyquinazolin-2-yl]piperidin-4-yl]piperidin-3-yl]methanol
Molecular weight	512.051
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.1
Synonyms	BDBM50265669 (1''-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinazolin-2-yl}-1,4''-bipiperidin-3-yl)methanol
Inchi Key	MMYMTFWMJSXBLE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H34ClN5O3/c1-35-24-14-22-23(15-25(24)36-2)30-27(31-26(22)29-20-7-5-19(28)6-8-20)32-12-9-21(10-13-32)33-11-3-4-18(16-33)17-34/h5-8,14-15,18,21,34H,3-4,9-13,16-17H2,1-2H3,(H,29,30,31)
PubChem CID	25212379
ChEMBL	CHEMBL496356
IUPHAR	N/A
BindingDB	50265669
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
209426	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
209427	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360

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