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| Name | Type-2 angiotensin II receptor |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | AGTR2 |
| Synonym | AT2 MRX88 Agtr2 angiotensin II receptor angiotensin II receptor, type 2 [ Show all ] |
| Disease | Postherpetic neuralgia Hypertension |
| Length | 363 |
| Amino acid sequence | MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS |
| UniProt | P50052 |
| Protein Data Bank | 5xjm, 5unh, 5ung, 5unf |
| GPCR-HGmod model | P50052 |
| 3D structure model | This structure is from PDB ID 5xjm. |
| BioLiP | BL0419199, BL0375199,BL0375200, BL0375198, BL0375196,BL0375197 |
| Therapeutic Target Database | T09909 |
| ChEMBL | CHEMBL4607 |
| IUPHAR | 35 |
| DrugBank | BE0003426 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 104 |  CHEMBL338434 | C36H41F4N5O6S | 747.807 | 11 / 2 | 7.3 | No |
| 557319 |  SCHEMBL16343432 | C29H28N2O3 | 452.554 | 4 / 1 | 2.5 | Yes |
| 557329 |  nocathiacin acid | C58H56N12O18S5 | 1369.45 | 30 / 9 | 1.9 | No |
| 846 |  CHEMBL315994 | C30H32N4O6S2 | 608.728 | 8 / 4 | 4.3 | No |
| 1547 |  CHEMBL306216 | C32H33FN8O2 | 580.668 | 9 / 2 | 2.8 | No |
| 2359 |  CHEMBL80370 | C26H31KN4O5S2 | 582.775 | 7 / 2 | N/A | No |
| 3205 |  TASOSARTAN | C23H21N7O | 411.469 | 6 / 1 | 3.0 | Yes |
| 3235 |  CHEMBL158557 | C33H29NO7 | 551.595 | 7 / 2 | 5.1 | No |
| 3540 |  CHEMBL74476 | C35H43N5O6S | 661.818 | 7 / 2 | 5.8 | No |
| 6208 |  CHEMBL3105385 | C22H33N5O4S | 463.597 | 6 / 3 | 3.0 | Yes |
| 6703 |  CHEMBL313005 | C30H40N4O6S2 | 616.792 | 8 / 3 | 5.1 | No |
| 9422 |  CHEMBL306922 | C34H37N7O4 | 607.715 | 8 / 2 | 5.7 | No |
| 10032 |  CHEMBL124771 | C33H37BrFN5O6S | 730.65 | 8 / 2 | 6.2 | No |
| 12484 |  CHEMBL74144 | C35H34FN5O6S | 671.744 | 9 / 2 | 5.5 | No |
| 12946 |  CHEMBL122157 | C31H33BrFN5O6S | 702.596 | 8 / 2 | 5.3 | No |
| 13956 |  CHEMBL504492 | C66H72N14O18S5 | 1509.68 | 31 / 8 | 4.3 | No |
| 14364 |  CHEMBL436396 | C32H35BrFN5O6S | 716.623 | 8 / 2 | 5.6 | No |
| 14369 |  CHEMBL70868 | C43H55FN4O7S | 790.992 | 9 / 1 | 8.9 | No |
| 15537 |  CHEMBL321313 | C33H37ClFN5O6S | 686.196 | 8 / 2 | 6.4 | No |
| 15629 |  CHEMBL348363 | C31H28N2O5 | 508.574 | 5 / 1 | 5.4 | No |
| 17179 |  CHEMBL309165 | C30H32N10O2 | 564.654 | 10 / 2 | 1.3 | No |
| 18475 |  CHEMBL3144487 | C63H93N17O12 | 1280.54 | 18 / 15 | -1.5 | No |
| 18476 |  ang I | C63H93N17O12 | 1280.54 | 18 / 15 | -1.5 | No |
| 18766 |  CHEMBL311386 | C34H40FN5O6S | 665.781 | 8 / 2 | 4.5 | No |
| 19956 |  CHEMBL74236 | C39H42FN3O6S2 | 731.898 | 9 / 1 | 9.2 | No |
| 20253 |  CHEMBL177435 | C27H24N6O | 448.53 | 5 / 1 | 5.1 | No |
| 20420 |  CHEMBL190811 | C26H30N4O4S2 | 526.67 | 7 / 1 | 6.0 | No |
| 21432 |  CHEMBL214671 | C27H29N3O5S2 | 539.665 | 7 / 1 | 5.6 | No |
| 21675 |  CHEMBL73283 | C41H44FN3O7S2 | 773.935 | 10 / 1 | 8.7 | No |
| 522120 |  CHEMBL3775436 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 522174 |  CHEMBL3775769 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 24459 |  CHEMBL155987 | C32H29NO5 | 507.586 | 5 / 1 | 5.6 | No |
| 24918 |  CHEMBL72409 | C31H35N9O | 549.683 | 8 / 2 | 3.5 | No |
| 27205 |  CHEMBL2203713 | C18H22N4S | 326.462 | 4 / 2 | 2.9 | Yes |
| 27869 |  CHEMBL314506 | C36H44N4O6S2 | 692.89 | 8 / 4 | 7.0 | No |
| 29269 |  CHEMBL3105395 | C19H22F3N3O5 | 429.396 | 9 / 3 | N/A | N/A |
| 30690 |  CHEMBL70793 | C41H44FN3O6S | 725.876 | 8 / 1 | 9.5 | No |
| 30847 |  CHEMBL334300 | C33H38ClN5O6S | 668.206 | 7 / 2 | 6.0 | No |
| 32935 |  CHEMBL156587 | C31H28N2O5 | 508.574 | 6 / 2 | 5.0 | No |
| 558282 |  SCHEMBL15148200 | C30H30N4O3 | 494.595 | 5 / 1 | 4.9 | Yes |
| 558324 |  CHEMBL508306 | C65H70N14O18S5 | 1495.66 | 31 / 9 | 3.9 | No |
| 35654 |  miconazole | C18H14Cl4N2O | 416.123 | 2 / 0 | 5.3 | No |
| 36244 |  CHEMBL219840 | C20H19N3O3 | 349.39 | 4 / 2 | 2.5 | Yes |
| 36462 |  CHEMBL2435834 | C33H31N3O3 | 517.629 | 4 / 2 | 6.9 | No |
| 38173 |  CHEMBL3105387 | C17H22N4O3 | 330.388 | 4 / 3 | 1.5 | Yes |
| 40786 |  CHEMBL339672 | C35H32Cl2FN5O5S | 724.629 | 7 / 2 | 7.0 | No |
| 44654 |  CHEMBL70770 | C27H31N7O4 | 517.59 | 8 / 3 | 4.0 | No |
| 45168 |  CHEMBL428986 | C50H64N12O11 | 1009.14 | 14 / 12 | -1.4 | No |
| 558679 |  CHEMBL507053 | C64H69N15O18S5 | 1496.64 | 31 / 10 | 3.3 | No |
| 45558 |  CHEMBL24688 | C28H28N6O3 | 496.571 | 7 / 1 | 4.5 | Yes |
| 46619 |  CHEMBL306362 | C36H42FN5O6S | 691.819 | 8 / 2 | 6.1 | No |
| 46669 |  CHEMBL290708 | C45H48N4O6S2 | 805.021 | 8 / 1 | 9.4 | No |
| 522885 |  CHEMBL3394207 | C25H31N3O4S | 469.6 | 5 / 1 | 5.2 | No |
| 46779 |  CHEMBL422756 | C27H26N6O | 450.546 | 5 / 1 | 4.9 | Yes |
| 48841 |  CHEMBL338888 | C33H37ClFN5O6S | 686.196 | 8 / 2 | 6.1 | No |
| 558792 |  CHEMBL510526 | C62H66N14O17S5 | 1439.59 | 30 / 9 | 3.9 | No |
| 50207 |  CHEMBL160930 | C32H28N2O7 | 552.583 | 7 / 0 | 5.8 | No |
| 50863 |  Angiotensin II, ala(8)- | C44H67N13O12 | 970.099 | 15 / 13 | -3.3 | No |
| 52498 |  CHEMBL70726 | C40H40FN3O7S | 725.832 | 9 / 1 | 8.4 | No |
| 52512 |  CHEMBL121872 | C34H39BrFN5O6S | 744.677 | 8 / 2 | 6.5 | No |
| 53212 |  CHEMBL331632 | C35H33ClFN5O6S | 706.186 | 8 / 2 | 6.4 | No |
| 523113 |  CHEMBL385433 | C50H71N13O12 | 1046.2 | 15 / 13 | -1.7 | No |
| 54283 |  CHEBI:58506 | C50H71N13O12 | 1046.2 | 13 / 12 | -0.4 | No |
| 56964 |  CHEMBL74556 | C36H44FN5O6S | 693.835 | 8 / 2 | 6.3 | No |
| 57543 |  CHEMBL415394 | C48H61N13O11 | 996.096 | 15 / 13 | -2.1 | No |
| 57655 |  CHEMBL125760 | C32H35ClFN5O7S | 688.168 | 9 / 2 | 5.0 | No |
| 59723 |  CHEMBL2435824 | C29H31N3O3 | 469.585 | 4 / 2 | 5.7 | No |
| 60837 |  CHEMBL341369 | C34H39BrFN5O6S | 744.677 | 8 / 2 | 6.5 | No |
| 444110 |  CHEMBL2370923 | C46H74N16O10 | 1011.2 | 14 / 14 | -3.5 | No |
| 61563 |  SCHEMBL604437 | C18H25N5O | 327.432 | 6 / 2 | 1.3 | Yes |
| 62081 |  CHEMBL80370 | C26H31N4O5S2- | 543.677 | 7 / 2 | 5.8 | No |
| 62082 |  CHEMBL76525 | C26H32N4O5S2 | 544.685 | 7 / 3 | 5.1 | No |
| 63276 |  CHEMBL25000 | C28H29N7O | 479.588 | 6 / 1 | 4.7 | Yes |
| 63645 |  CHEMBL217053 | C18H13BrN2O4 | 401.216 | 5 / 1 | 3.5 | Yes |
| 64416 |  CHEMBL309365 | C39H40N8O2 | 652.803 | 8 / 2 | 4.7 | No |
| 66403 |  CHEMBL289306 | C30H38N4O3S2 | 566.779 | 6 / 1 | 7.3 | No |
| 67239 |  CHEMBL263191 | C34H40FN5O6S | 665.781 | 8 / 3 | 4.7 | No |
| 67458 |  CHEMBL3105382 | C22H31N5O4 | 429.521 | 5 / 3 | 2.9 | Yes |
| 523525 |  CHEMBL3394209 | C25H31N3O4S | 469.6 | 5 / 1 | 5.2 | No |
| 69418 |  hemopressin | C53H77N13O12 | 1088.28 | 15 / 14 | -2.0 | No |
| 70074 |  CHEMBL315275 | C28H36N4O6S2 | 588.738 | 8 / 4 | 4.4 | No |
| 72990 |  CHEMBL273992 | C34H37N7O4 | 607.715 | 8 / 2 | 6.1 | No |
| 74770 |  CHEMBL406907 | C50H61N11O12 | 1008.1 | 15 / 11 | -0.9 | No |
| 75281 |  CHEMBL307321 | C36H44N6O5S | 672.845 | 9 / 2 | 3.4 | No |
| 75529 |  CHEMBL122380 | C35H31BrF3N5O5S | 770.622 | 9 / 2 | 6.7 | No |
| 76427 |  CHEMBL165572 | C23H20F6N4O2S | 530.489 | 12 / 2 | 6.0 | No |
| 78534 |  CHEMBL156129 | C33H31NO5 | 521.613 | 5 / 1 | 6.1 | No |
| 79306 |  BDBM50049190 | C35H38N4O5S | 626.772 | 7 / 1 | 7.5 | No |
| 80278 |  CHEMBL309081 | C43H39N7O3 | 701.831 | 7 / 1 | 8.7 | No |
| 81672 |  CHEMBL331455 | C33H35F4N5O6S | 705.726 | 11 / 2 | 6.2 | No |
| 82023 |  CHEMBL291125 | C36H40N4O6S3 | 720.918 | 9 / 2 | 7.7 | No |
| 82392 |  CHEMBL71069 | C40H42N4O7S | 722.857 | 8 / 2 | 7.2 | No |
| 82785 |  CHEMBL311253 | C38H41FN4O8S | 732.824 | 10 / 1 | 7.1 | No |
| 85494 |  CHEMBL311160 | C36H35F2N5O5S | 687.763 | 8 / 3 | 5.7 | No |
| 86087 |  CHEMBL3105466 | C24H29N5O5S | 499.586 | 7 / 3 | 2.8 | Yes |
| 86246 |  CHEMBL3105389 | C19H23F3N4O2 | 396.414 | 6 / 2 | 3.1 | Yes |
| 86839 |  CHEMBL350875 | C32H30N2O5 | 522.601 | 6 / 1 | 5.3 | No |
| 445175 |  CHEMBL2370903 | C45H71N13O11 | 970.143 | 14 / 12 | -2.4 | No |
| 87683 |  CHEMBL304620 | C33H44N4O6S | 624.797 | 7 / 2 | 5.3 | No |
| 88225 |  CHEMBL414478 | C53H68N14O12 | 1093.21 | 16 / 13 | -2.1 | No |
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