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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL290708
Molecular formula	C45H48N4O6S2
IUPAC name	butyl N-[3-[4-[[6-[benzoyl(benzyl)amino]-4-oxo-2-propylquinazolin-3-yl]methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate
Molecular weight	805.021
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	9.4
Synonyms	BDBM50141056 N-Butyloxycarbonyl-5-isobutyl-3-{4-[6-(N-benzoyl-benzylamino)-4-oxo-2-propyl-4H-quinazolin-3-ylmethyl]phenyl}-thiophene-2-sulfonamide
Inchi Key	COHIQUMUMWMOJY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C45H48N4O6S2/c1-5-7-25-55-45(52)47-57(53,54)44-38(28-37(56-44)26-31(3)4)34-21-19-33(20-22-34)30-49-41(14-6-2)46-40-24-23-36(27-39(40)43(49)51)48(29-32-15-10-8-11-16-32)42(50)35-17-12-9-13-18-35/h8-13,15-24,27-28,31H,5-7,14,25-26,29-30H2,1-4H3,(H,47,52)
PubChem CID	11274375
ChEMBL	CHEMBL290708
IUPHAR	N/A
BindingDB	50141056
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
46669	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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