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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL70868
Molecular formula	C43H55FN4O7S
IUPAC name	[4-[benzyl(butyl)amino]-4-oxobutyl] 5-ethyl-3-[[2-fluoro-4-[2-(3-methylbutoxycarbonylsulfamoyl)phenyl]phenyl]methyl]-2-propylimidazole-4-carboxylate
Molecular weight	790.992
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	8.9
Synonyms	BDBM50283203
Inchi Key	ATVZZAXDSVBSGX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C43H55FN4O7S/c1-6-9-25-47(29-32-17-11-10-12-18-32)40(49)21-15-26-54-42(50)41-37(8-3)45-39(16-7-2)48(41)30-34-23-22-33(28-36(34)44)35-19-13-14-20-38(35)56(52,53)46-43(51)55-27-24-31(4)5/h10-14,17-20,22-23,28,31H,6-9,15-16,21,24-27,29-30H2,1-5H3,(H,46,51)
PubChem CID	44311582
ChEMBL	CHEMBL70868
IUPHAR	N/A
BindingDB	50283203
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14370	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
14369	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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