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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL321313
Molecular formula	C33H37ClFN5O6S
IUPAC name	ethyl N-[2-[4-[[1-(5-acetamido-2-chlorophenyl)-3-butyl-5-oxo-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]-4-propylphenyl]sulfonylcarbamate
Molecular weight	686.196
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	6.4
Synonyms	N-{3-[3-Butyl-4-(3-fluoro-2''-(ethyloxtycarbonyl)sulfamoyl-5''-propyl-biphenyl-4-ylmethyl)-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl]-4-chloro-phenyl}-acetamide SCHEMBL9399763 BDBM50283765
Inchi Key	AVPYNETYRCMACW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H37ClFN5O6S/c1-5-8-10-31-37-40(29-19-25(36-21(4)41)14-15-27(29)34)33(43)39(31)20-24-13-12-23(18-28(24)35)26-17-22(9-6-2)11-16-30(26)47(44,45)38-32(42)46-7-3/h11-19H,5-10,20H2,1-4H3,(H,36,41)(H,38,42)
PubChem CID	10417195
ChEMBL	CHEMBL321313
IUPHAR	N/A
BindingDB	50283765
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15538	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
15539	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
15537	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363
15540	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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