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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL510526
Molecular formula	C62H66N14O17S5
IUPAC name	N-[2-(dimethylamino)ethyl]-2-[(1S,18S,21E,28S,29S,30S)-30-[(2S,4S,5R,6S)-5-(dimethylamino)-4-hydroxy-4,6-dimethyloxan-2-yl]oxy-9,52-dihydroxy-18-[(1R)-1-hydroxyethyl]-21-(1-methoxyethylidene)-16,19,26,31,42,46-hexaoxo-32,43,54-trioxa-3,13,23,49-tetrathia-7,17,20,27,45,51,52,55,56,57-decazadecacyclo[26.16.6.229,40.12,5.112,15.122,25.138,41.147,50.06,11.034,39]heptapentaconta-2(57),4,6,8,10,12(56),14,22(55),24,34(39),35,37,40,47,50-pentadecaen-8-yl]-1,3-thiazole-4-carboxamide
Molecular weight	1439.59
Hydrogen bond acceptor	30
Hydrogen bond donor	9
XlogP	3.9
Synonyms	BDBM50258825
Inchi Key	CSEXVIOYIBKSFG-OSMKVLJESA-N
Inchi ID	InChI=1S/C62H66N14O17S5/c1-25(77)41-54(83)72-42(26(2)88-9)57-68-36(24-96-57)53(82)73-45-47-48(93-39-16-62(4,86)49(75(7)8)27(3)92-39)61(85)90-17-28-11-10-12-37-40(28)30(18-89-47)46(76(37)87)60(84)91-19-31(64-51(80)34-23-98-59(45)69-34)56-65-32(20-95-56)43-29(55-66-35(22-94-55)52(81)71-41)15-38(78)44(70-43)58-67-33(21-97-58)50(79)63-13-14-74(5)6/h10-12,15,20-25,27,31,39,41,45,47-49,77-78,86-87H,13-14,16-19H2,1-9H3,(H,63,79)(H,64,80)(H,71,81)(H,72,83)(H,73,82)/b42-26+/t25-,27+,31+,39+,41+,45+,47+,48+,49-,62+/m1/s1
PubChem CID	136059719
ChEMBL	CHEMBL510526
IUPHAR	N/A
BindingDB	50258825
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558792	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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