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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL311160
Molecular formula	C36H35F2N5O5S
IUPAC name	4-ethyl-N-[2-[4-[[2-ethyl-4-oxo-6-(propan-2-ylcarbamoylamino)quinazolin-3-yl]methyl]-3-fluorophenyl]phenyl]sulfonyl-2-fluorobenzamide
Molecular weight	687.763
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	5.7
Synonyms	BDBM50283312 4''-[2-Ethyl-6-(3-isopropyl-ureido)-4-oxo-4H-quinazolin-3-ylmethyl]-3''-fluoro-biphenyl-2-sulfonic acid 4-ethyl-2-fluoro-benzoylamide
Inchi Key	FRKWBPZUTQTJCZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C36H35F2N5O5S/c1-5-22-11-15-27(30(38)17-22)34(44)42-49(47,48)32-10-8-7-9-26(32)23-12-13-24(29(37)18-23)20-43-33(6-2)41-31-16-14-25(19-28(31)35(43)45)40-36(46)39-21(3)4/h7-19,21H,5-6,20H2,1-4H3,(H,42,44)(H2,39,40,46)
PubChem CID	44315351
ChEMBL	CHEMBL311160
IUPHAR	N/A
BindingDB	50283312
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
85493	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
85496	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
85494	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363
85495	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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