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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL74236
Molecular formula	C39H42FN3O6S2
IUPAC name	(2-thiophen-3-ylphenyl)methyl 5-ethyl-3-[[2-fluoro-4-[2-(3-methylbutoxycarbonylsulfamoyl)phenyl]phenyl]methyl]-2-propylimidazole-4-carboxylate
Molecular weight	731.898
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	9.2
Synonyms	BDBM50283229
Inchi Key	BBYKQNJKFVTGSO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C39H42FN3O6S2/c1-5-11-36-41-34(6-2)37(38(44)49-24-29-12-7-8-13-31(29)30-19-21-50-25-30)43(36)23-28-17-16-27(22-33(28)40)32-14-9-10-15-35(32)51(46,47)42-39(45)48-20-18-26(3)4/h7-10,12-17,19,21-22,25-26H,5-6,11,18,20,23-24H2,1-4H3,(H,42,45)
PubChem CID	44311558
ChEMBL	CHEMBL74236
IUPHAR	N/A
BindingDB	50283229
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19957	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
19956	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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