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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL125760
Molecular formula	C32H35ClFN5O7S
IUPAC name	tert-butyl N-[2-[4-[[1-[2-chloro-5-[(2-ethoxyacetyl)amino]phenyl]-3-ethyl-5-oxo-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]phenyl]sulfonylcarbamate
Molecular weight	688.168
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	5.0
Synonyms	SCHEMBL9241026 BDBM50030708 N-{4-Chloro-3-[3-ethyl-4-(3-fluoro-2''-(N-t-butyloxycarbonyl)-Sulfanamido-biphenyl-4-ylmethyl)-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl]-phenyl}-2-ethoxy-acetamide
Inchi Key	DECHRKDVEZQXQI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H35ClFN5O7S/c1-6-28-36-39(26-17-22(14-15-24(26)33)35-29(40)19-45-7-2)31(42)38(28)18-21-13-12-20(16-25(21)34)23-10-8-9-11-27(23)47(43,44)37-30(41)46-32(3,4)5/h8-17H,6-7,18-19H2,1-5H3,(H,35,40)(H,37,41)
PubChem CID	10394859
ChEMBL	CHEMBL125760
IUPHAR	N/A
BindingDB	50030708
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
57654	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
57657	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
57655	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363
57656	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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