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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL122157
Molecular formula	C31H33BrFN5O6S
IUPAC name	tert-butyl N-[2-[4-[[1-[2-bromo-5-(propanoylamino)phenyl]-3-ethyl-5-oxo-1,2,4-triazol-4-yl]methyl]-3-fluorophenyl]phenyl]sulfonylcarbamate
Molecular weight	702.596
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.3
Synonyms	SCHEMBL9120438 BDBM50030723 N-{4-Bromo-3-[3-ethyl-4-(3-fluoro-2''-(N-t-butyloxycarbonyl)-Sulfanamido-biphenyl-4-ylmethyl)-5-oxo-4,5-dihydro-[1,2,4]triazol-1-yl]-phenyl}-propionamide
Inchi Key	ARZSHBUQUYOQDP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H33BrFN5O6S/c1-6-27-35-38(25-17-21(14-15-23(25)32)34-28(39)7-2)30(41)37(27)18-20-13-12-19(16-24(20)33)22-10-8-9-11-26(22)45(42,43)36-29(40)44-31(3,4)5/h8-17H,6-7,18H2,1-5H3,(H,34,39)(H,36,40)
PubChem CID	10417321
ChEMBL	CHEMBL122157
IUPHAR	N/A
BindingDB	50030723
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12944	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
12947	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
12945	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363
12946	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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