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Name | C-C chemokine receptor type 10 |
---|---|
Species | Homo sapiens (Human) |
Gene | CCR10 |
Synonym | CCR-10 CCR10 CC-CKR-10 G-protein coupled receptor 2 GPR-2 [ Show all ] |
Disease | Inflammatory disease |
Length | 362 |
Amino acid sequence | MGTEATEQVSWGHYSGDEEDAYSAEPLPELCYKADVQAFSRAFQPSVSLTVAALGLAGNGLVLATHLAARRAARSPTSAHLLQLALADLLLALTLPFAAAGALQGWSLGSATCRTISGLYSASFHAGFLFLACISADRYVAIARALPAGPRPSTPGRAHLVSVIVWLLSLLLALPALLFSQDGQREGQRRCRLIFPEGLTQTVKGASAVAQVALGFALPLGVMVACYALLGRTLLAARGPERRRALRVVVALVAAFVVLQLPYSLALLLDTADLLAARERSCPASKRKDVALLVTSGLALARCGLNPVLYAFLGLRFRQDLRRLLRGGSCPSGPQPRRGCPRRPRLSSCSAPTETHSLSWDN |
UniProt | P46092 |
Protein Data Bank | N/A |
GPCR-HGmod model | P46092 |
3D structure model | This predicted structure model is from GPCR-EXP P46092. |
BioLiP | N/A |
Therapeutic Target Database | T71054 |
ChEMBL | CHEMBL2321628 |
IUPHAR | 67 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
521447 | CHEMBL3731686 | C27H26Cl2FN7O4S | 634.508 | 8 / 3 | 4.7 | No |
535954 | CHEMBL3959737 | C21H25Cl2N5O3S | 498.423 | 6 / 2 | 3.6 | Yes |
521518 | CHEMBL3727384 | C27H26Cl2FN7O4S | 634.508 | 8 / 3 | 4.7 | No |
536042 | CHEMBL3923733 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
521603 | CHEMBL3733065 | C29H30FN7O5S | 607.661 | 9 / 3 | 2.9 | No |
536151 | CHEMBL3919363 | C20H24Cl2N6O3S | 499.411 | 7 / 2 | 2.7 | Yes |
521742 | CHEMBL3729731 | C29H30FN7O5S | 607.661 | 9 / 3 | 2.9 | No |
521924 | CHEMBL3732878 | C28H28ClFN6O3S | 583.079 | 8 / 2 | 5.1 | No |
522014 | CHEMBL3730003 | C28H26ClFN6O4S | 597.062 | 8 / 2 | 4.4 | No |
536491 | CHEMBL3960700 | C22H25N5O4S | 455.533 | 6 / 3 | 1.2 | Yes |
522314 | CHEMBL3731390 | C30H29ClN6O5S | 621.109 | 8 / 2 | 3.7 | No |
522403 | CHEMBL3731840 | C25H23Cl2FN6O4S | 593.455 | 9 / 2 | 4.8 | No |
553415 | eut-22 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
536781 | CHEMBL3889627 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
522594 | CHEMBL3728353 | C29H29FN6O5S | 592.646 | 9 / 2 | 3.2 | No |
536985 | CHEMBL3943972 | C18H24Cl2N6O3S | 475.389 | 7 / 2 | 2.6 | Yes |
522726 | CHEMBL3728979 | C27H24F4N6O4S | 604.581 | 11 / 2 | 4.8 | No |
537039 | CHEMBL3948828 | C19H25Cl2N5O3S | 474.401 | 6 / 2 | 2.6 | Yes |
537045 | CHEMBL3971886 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
522939 | CHEMBL3728246 | C25H21Cl2FN6O4S | 591.439 | 8 / 2 | 4.6 | No |
522962 | CHEMBL3729606 | C28H28ClF2N7O4S | 632.084 | 9 / 3 | 4.6 | No |
522978 | CHEMBL3728616 | C27H28ClFN6O4S | 587.067 | 9 / 2 | 4.0 | No |
523236 | CHEMBL3731147 | C30H32FN7O5S | 621.688 | 9 / 2 | 3.3 | No |
523268 | CHEMBL3728071 | C28H23Cl2FN8O3S | 641.503 | 10 / 2 | 4.6 | No |
523507 | CHEMBL3731775 | C30H29ClN6O5S | 621.109 | 8 / 2 | 3.7 | No |
523700 | CHEMBL3731933 | C29H29FN6O5S | 592.646 | 9 / 2 | 3.2 | No |
523840 | CHEMBL3732508 | C30H29FN6O5S | 604.657 | 9 / 2 | 3.1 | No |
523868 | CHEMBL3728121 | C29H29ClN6O5S | 609.098 | 8 / 2 | 3.7 | No |
524014 | CHEMBL3731832 | C32H34ClN7O6S | 680.177 | 9 / 3 | 4.0 | No |
538137 | CHEMBL3909737 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
548932 | CHEMBL3932155 | C19H24Cl2N6O5S | 519.398 | 8 / 2 | 2.5 | No |
548933 | CHEMBL3908983 | C19H24Cl2N6O5S | 519.398 | 8 / 2 | 2.5 | No |
538193 | CHEMBL3908230 | C19H24Cl2N6O5S | 519.398 | 8 / 2 | 2.5 | No |
524127 | CHEMBL3731438 | C28H30FN7O4S | 579.651 | 8 / 3 | 3.9 | No |
524167 | CHEMBL3733165 | C28H23Cl2FN8O3S | 641.503 | 10 / 2 | 4.9 | No |
538296 | CHEMBL3942284 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
524254 | CHEMBL3728606 | C28H28ClFN6O4S | 599.078 | 8 / 2 | 4.8 | No |
538400 | CHEMBL3945769 | C24H29N5O3S | 467.588 | 5 / 1 | 2.6 | Yes |
524987 | CHEMBL3730752 | C26H23F3N6O4S | 572.563 | 10 / 2 | 3.5 | No |
539149 | CHEMBL3979967 | C19H24Cl3N5O3S | 508.843 | 6 / 2 | 3.6 | No |
539191 | CHEMBL3933303 | C23H31N5O3S | 457.593 | 6 / 2 | 2.6 | Yes |
525211 | CHEMBL3732652 | C28H30FN7O3S2 | 595.712 | 8 / 3 | 4.5 | No |
525304 | CHEMBL3732876 | C29H30ClN7O5S | 624.113 | 8 / 3 | 3.4 | No |
525327 | CHEMBL3732868 | C26H23Cl2FN6O4S | 605.466 | 8 / 2 | 4.6 | No |
525394 | CHEMBL3729178 | C28H28ClFN8O4S | 627.092 | 9 / 3 | 3.7 | No |
525500 | CHEMBL3729146 | C27H27FN6O4S | 550.609 | 8 / 2 | 3.7 | No |
525578 | CHEMBL3731219 | C27H25Cl2FN6O4S | 619.493 | 8 / 2 | 5.0 | No |
525605 | CHEMBL3727497 | C28H27ClFN7O4S | 612.077 | 9 / 2 | 4.0 | No |
525709 | CHEMBL3732344 | C28H25ClF4N6O4S | 653.05 | 11 / 2 | 5.3 | No |
549797 | CHEMBL3928968 | C19H21Cl2N5O3S | 470.369 | 6 / 2 | 2.3 | Yes |
549812 | CHEMBL3950532 | C18H24Cl2N6O3S | 475.389 | 7 / 2 | 2.1 | Yes |
539879 | CHEMBL3969321 | C20H23Cl2N5O3S | 484.396 | 6 / 2 | 2.6 | Yes |
525940 | CHEMBL3728332 | C28H30FN7O4S | 579.651 | 9 / 3 | 3.3 | No |
526177 | CHEMBL3731138 | C29H30N6O4S | 558.657 | 7 / 2 | 3.6 | No |
526298 | CHEMBL3730468 | C28H29FN6O5S | 580.635 | 9 / 2 | 3.5 | No |
526435 | CHEMBL3729372 | C27H28F2N6O3S | 554.617 | 9 / 2 | 4.3 | No |
526523 | CHEMBL3727981 | C26H27FN6O5S2 | 586.657 | 10 / 2 | 3.4 | No |
526804 | CHEMBL3732672 | C27H26ClF2N7O4S | 618.057 | 9 / 3 | 4.2 | No |
526823 | CHEMBL3732501 | C27H28ClFN6O3S | 571.068 | 8 / 2 | 4.9 | No |
526863 | CHEMBL3730497 | C28H31N7O4S | 561.661 | 7 / 3 | 3.3 | No |
550245 | CHEMBL3973467 | C18H24Cl2N6O3S | 475.389 | 7 / 2 | 2.4 | Yes |
527155 | CHEMBL3731456 | C28H26ClF2N7O4S | 630.068 | 9 / 3 | 5.0 | No |
550311 | CHEMBL3964878 | C22H27Cl2N3O3S | 484.436 | 5 / 2 | 4.6 | Yes |
541068 | CHEMBL3926111 | C22H27Cl2N3O3S | 484.436 | 5 / 2 | 4.6 | Yes |
550329 | CHEMBL3979899 | C19H21N5O3S | 399.469 | 5 / 2 | 1.4 | Yes |
527288 | CHEMBL3728893 | C29H29F2N7O4S | 609.653 | 9 / 3 | 4.7 | No |
550419 | CHEMBL3900672 | C17H19Cl2N5O3S | 444.331 | 6 / 2 | 1.8 | Yes |
527463 | CHEMBL3728376 | C27H27ClFN7O4S | 600.066 | 8 / 3 | 4.1 | No |
541524 | CHEMBL3975141 | C25H28N4O3S | 464.584 | 5 / 1 | 3.8 | Yes |
527762 | N-[7-(4-fluoro-2-methylphenylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidin-3-ylsulfonyl]cyclopropanecarboxamide | C29H29FN6O4S | 576.647 | 8 / 2 | 4.1 | No |
528222 | CHEMBL3728115 | C27H28ClN7O4S | 582.076 | 7 / 3 | 4.0 | No |
542337 | CHEMBL3951650 | C20H24Cl2N6O3S | 499.411 | 7 / 2 | 2.4 | Yes |
528670 | CHEMBL3733183 | C26H21Cl2FN8O3S2 | 647.525 | 11 / 2 | 5.1 | No |
528730 | CHEMBL3732275 | C29H27Cl2FN6O5S | 661.53 | 9 / 2 | 4.5 | No |
542684 | CHEMBL3890608 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
528971 | CHEMBL3733316 | C26H25ClN6O5S | 569.033 | 8 / 2 | 4.2 | No |
529049 | CHEMBL3731999 | C32H30FN7O4S | 627.695 | 8 / 3 | 5.6 | No |
542989 | CHEMBL3971826 | C22H25N5O3S | 439.534 | 5 / 2 | 2.2 | Yes |
529096 | CHEMBL3729920 | C26H23Cl2FN6O4S | 605.466 | 8 / 2 | 4.6 | No |
529097 | CHEMBL3728619 | C27H26ClF2N7O4S | 618.057 | 9 / 3 | 4.2 | No |
529272 | CHEMBL3728998 | C26H25ClFN7O4S | 586.039 | 8 / 3 | 3.7 | No |
529619 | CHEMBL3731666 | C28H30FN7O3S | 563.652 | 8 / 1 | 4.1 | No |
529693 | CHEMBL3727493 | C27H25F5N6O3S | 608.588 | 12 / 2 | 5.1 | No |
529838 | CHEMBL3728415 | C28H30N6O5S | 562.645 | 8 / 2 | 4.3 | No |
530021 | CHEMBL3730157 | C28H28ClFN6O4S | 599.078 | 8 / 2 | 4.8 | No |
544263 | CHEMBL3940706 | C20H26Cl2N4O3S | 473.413 | 5 / 2 | 3.0 | Yes |
544327 | CHEMBL3964547 | C19H24Cl3N5O3S | 508.843 | 6 / 2 | 3.3 | No |
530407 | CHEMBL3733128 | C27H27FN6O5S | 566.608 | 9 / 3 | 3.0 | No |
530445 | CHEMBL3732824 | C29H26Cl2N6O5S | 641.524 | 8 / 2 | 3.9 | No |
530456 | CHEMBL3729504 | C27H25F3N6O4S | 586.59 | 10 / 2 | 4.0 | No |
530457 | CHEMBL3727436 | C28H29ClFN7O4S | 614.093 | 8 / 3 | 4.5 | No |
544681 | CHEMBL3955499 | C21H25Cl2N5O3S | 498.423 | 6 / 2 | 3.1 | Yes |
530703 | CHEMBL3731872 | C29H27ClF2N6O4S | 629.08 | 9 / 2 | 4.8 | No |
544839 | CHEMBL3946799 | C21H22Cl2F3N5O3S | 552.394 | 9 / 2 | 3.7 | No |
552025 | CHEMBL3944089 | C19H25Cl2N5O3S | 474.401 | 6 / 2 | 2.4 | Yes |
530861 | CHEMBL3732278 | C28H27ClN6O5S | 595.071 | 8 / 2 | 3.2 | No |
530943 | CHEMBL3731105 | C28H28F2N6O4S | 582.627 | 9 / 2 | 4.2 | No |
531009 | CHEMBL3732825 | C28H26ClFN6O5S | 613.061 | 9 / 2 | 3.4 | No |
545163 | CHEMBL3891692 | C23H24F3N5O3S | 507.532 | 8 / 2 | 3.2 | No |
545262 | CHEMBL3891289 | C22H26Cl3N3O3S | 518.878 | 5 / 2 | 5.2 | No |
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