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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3727493
Molecular formula	C27H25F5N6O3S
IUPAC name	7-(4-fluoro-2-methylanilino)-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]-N-(2,2,2-trifluoroethyl)pyrazolo[1,5-a]pyrimidine-3-sulfonamide
Molecular weight	608.588
Hydrogen bond acceptor	12
Hydrogen bond donor	2
XlogP	5.1
Synonyms	7-(4-fluoro-2-methylphenylamino)-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]-N-(2,2,2-trifluoroethyl)pyrazolo[1,5-a]pyrimidine-3-sulfonamide QURQYSNPKJFMGS-UHFFFAOYSA-N SCHEMBL14471955
Inchi Key	QURQYSNPKJFMGS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H25F5N6O3S/c1-16-12-20(29)6-7-22(16)36-24-21(26(39)37-10-8-18(9-11-37)17-2-4-19(28)5-3-17)13-33-25-23(14-34-38(24)25)42(40,41)35-15-27(30,31)32/h2-7,12-14,18,35-36H,8-11,15H2,1H3
PubChem CID	53379326
ChEMBL	CHEMBL3727493
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
529693	C-C chemokine receptor type 10	P46092	CCR10	Homo sapiens (Human)	362

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