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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	C-C chemokine receptor type 10
Species	Homo sapiens (Human)
Gene	CCR10
Synonym	CCR-10 CCR10 CC-CKR-10 G-protein coupled receptor 2 GPR-2 C-C CKR-10 [ Show all ]
Disease	Inflammatory disease
Length	362
Amino acid sequence	MGTEATEQVSWGHYSGDEEDAYSAEPLPELCYKADVQAFSRAFQPSVSLTVAALGLAGNGLVLATHLAARRAARSPTSAHLLQLALADLLLALTLPFAAAGALQGWSLGSATCRTISGLYSASFHAGFLFLACISADRYVAIARALPAGPRPSTPGRAHLVSVIVWLLSLLLALPALLFSQDGQREGQRRCRLIFPEGLTQTVKGASAVAQVALGFALPLGVMVACYALLGRTLLAARGPERRRALRVVVALVAAFVVLQLPYSLALLLDTADLLAARERSCPASKRKDVALLVTSGLALARCGLNPVLYAFLGLRFRQDLRRLLRGGSCPSGPQPRRGCPRRPRLSSCSAPTETHSLSWDN
UniProt	P46092
Protein Data Bank	N/A
GPCR-HGmod model	P46092
3D structure model	This predicted structure model is from GPCR-EXP P46092.
BioLiP	N/A
Therapeutic Target Database	T71054
ChEMBL	CHEMBL2321628
IUPHAR	67
DrugBank	N/A

Ligand

Name	CHEMBL3731138
Molecular formula	C29H30N6O4S
IUPAC name	N-[7-(benzylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidin-3-yl]sulfonylcyclopropanecarboxamide
Molecular weight	558.657
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.6
Synonyms	SCHEMBL15915150
Inchi Key	JYWZIFJYQIQRTH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H30N6O4S/c36-28(23-11-12-23)33-40(38,39)25-19-32-35-26(30-17-20-7-3-1-4-8-20)24(18-31-27(25)35)29(37)34-15-13-22(14-16-34)21-9-5-2-6-10-21/h1-10,18-19,22-23,30H,11-17H2,(H,33,36)
PubChem CID	90312638
ChEMBL	CHEMBL3731138
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	89.4 %	None	ChEMBL

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