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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3733183
Molecular formula	C26H21Cl2FN8O3S2
IUPAC name	7-(2,5-dichloroanilino)-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]-N-(1,3,4-thiadiazol-2-yl)pyrazolo[1,5-a]pyrimidine-3-sulfonamide
Molecular weight	647.525
Hydrogen bond acceptor	11
Hydrogen bond donor	2
XlogP	5.1
Synonyms	SCHEMBL15915652
Inchi Key	OSXXXLRTSIMZRN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H21Cl2FN8O3S2/c27-17-3-6-20(28)21(11-17)33-23-19(25(38)36-9-7-16(8-10-36)15-1-4-18(29)5-2-15)12-30-24-22(13-32-37(23)24)42(39,40)35-26-34-31-14-41-26/h1-6,11-14,16,33H,7-10H2,(H,34,35)
PubChem CID	90313007
ChEMBL	CHEMBL3733183
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
528670	C-C chemokine receptor type 10	P46092	CCR10	Homo sapiens (Human)	362

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