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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3727436
Molecular formula	C28H29ClFN7O4S
IUPAC name	1-[7-(2-chloro-5-methylanilino)-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidin-3-yl]sulfonyl-3-ethylurea
Molecular weight	614.093
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	4.5
Synonyms	7-(2-Chloro-5-methylanilino)-N-(ethylcarbamoyl)-6-[[4-(4-fluorophenyl)piperidino]carbonyl]pyrazolo[1,5-a]pyrimidine-3-sulfonamide SCHEMBL14471851
Inchi Key	SLPKOJIFSYDSPG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H29ClFN7O4S/c1-3-31-28(39)35-42(40,41)24-16-33-37-25(34-23-14-17(2)4-9-22(23)29)21(15-32-26(24)37)27(38)36-12-10-19(11-13-36)18-5-7-20(30)8-6-18/h4-9,14-16,19,34H,3,10-13H2,1-2H3,(H2,31,35,39)
PubChem CID	71178991
ChEMBL	CHEMBL3727436
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
530457	C-C chemokine receptor type 10	P46092	CCR10	Homo sapiens (Human)	362

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