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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3732344
Molecular formula	C28H25ClF4N6O4S
IUPAC name	N-[7-[2-chloro-5-(trifluoromethyl)anilino]-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidin-3-yl]sulfonylpropanamide
Molecular weight	653.05
Hydrogen bond acceptor	11
Hydrogen bond donor	2
XlogP	5.3
Synonyms	IZNAAPQWDYCIMT-UHFFFAOYSA-N N-{7-(2-chloro-5-trifluoromethylphenylamino)-6-[4-(4-fluorophenyl)piperidine-1-carbonyl]pyrazolo[1,5-a]pyrimidin-3-ylsulfonyl}propionamide SCHEMBL14471862
Inchi Key	IZNAAPQWDYCIMT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H25ClF4N6O4S/c1-2-24(40)37-44(42,43)23-15-35-39-25(36-22-13-18(28(31,32)33)5-8-21(22)29)20(14-34-26(23)39)27(41)38-11-9-17(10-12-38)16-3-6-19(30)7-4-16/h3-8,13-15,17,36H,2,9-12H2,1H3,(H,37,40)
PubChem CID	71178997
ChEMBL	CHEMBL3732344
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
525709	C-C chemokine receptor type 10	P46092	CCR10	Homo sapiens (Human)	362

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