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Name | Adenosine receptor A3 |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Adora3 |
Synonym | A3 receptor A3AR Adenosine receptor A3 ARA3 TGPCR1 |
Disease | N/A for non-human GPCRs |
Length | 320 |
Amino acid sequence | MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE |
UniProt | P28647 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3360 |
IUPHAR | 21 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
653 | CHEMBL323403 | C24H23NO3S | 405.512 | 5 / 0 | 5.9 | No |
521464 | CHEMBL3827623 | C26H36N6O3 | 480.613 | 6 / 0 | 3.9 | Yes |
1205 | CHEMBL178846 | C22H25ClN6O5 | 488.929 | 9 / 4 | 1.3 | Yes |
3857 | 316173-57-6 | C20H19N7O2 | 389.419 | 7 / 1 | 2.7 | Yes |
4603 | CHEMBL3125715 | C22H29N5O2 | 395.507 | 6 / 3 | 3.1 | Yes |
4752 | CHEMBL27376 | C20H20ClIN6O3 | 554.773 | 7 / 4 | 2.0 | No |
6721 | CHEMBL608327 | C18H18ClIN6O4 | 544.734 | 8 / 4 | 1.5 | No |
7419 | CHEMBL380914 | C19H19Cl2N7O5 | 496.305 | 8 / 5 | 1.3 | Yes |
8515 | CHEMBL206807 | C22H27N7O6 | 485.501 | 9 / 5 | 0.6 | Yes |
8518 | CHEMBL610394 | C22H27N7O6 | 485.501 | 9 / 5 | 0.6 | Yes |
10225 | CHEMBL413046 | C26H31N7O6 | 537.577 | 9 / 5 | 2.0 | No |
11438 | CHEMBL2113704 | C16H15IN6 | 418.242 | 5 / 1 | 2.7 | Yes |
11517 | CHEMBL2113685 | C16H18IN5O2S | 471.317 | 7 / 3 | 2.0 | Yes |
14168 | CHEMBL2113702 | C13H11ClIN5 | 399.62 | 4 / 1 | 3.5 | Yes |
16714 | CHEMBL95384 | C15H11FN2O | 254.264 | 4 / 1 | 3.0 | Yes |
17483 | CHEMBL383548 | C20H20Cl2N6O5 | 495.317 | 8 / 4 | 1.2 | Yes |
20224 | CHEMBL2112597 | C10H14N6O | 234.263 | 6 / 3 | -0.1 | Yes |
522081 | CHEMBL3751909 | C25H19N5O2 | 421.46 | 5 / 1 | 4.4 | Yes |
22453 | CHEMBL218326 | C18H19N9O4 | 425.409 | 11 / 4 | -0.9 | No |
23107 | 2-methyl-7-phenyl-1,8-naphthyridine | C15H12N2 | 220.275 | 2 / 0 | 3.5 | Yes |
24131 | 168279-54-7 | C12H14O3S2 | 270.361 | 5 / 0 | 3.1 | Yes |
24604 | CHEMBL2113562 | C19H22IN7O4 | 539.334 | 9 / 5 | 1.2 | No |
24836 | CHEMBL2112076 | C10H12ClN5O4 | 301.687 | 8 / 4 | -0.1 | Yes |
24851 | 2-Chloroadenosine | C10H12ClN5O4 | 301.687 | 8 / 4 | -0.1 | Yes |
25398 | CHEMBL574212 | C60H69ClN10O8S | 1125.78 | 13 / 6 | 6.3 | No |
25509 | CHEMBL439976 | C18H19ClIN7O2 | 527.751 | 7 / 3 | 2.0 | No |
26374 | CHEMBL115608 | C16H24N4O4 | 336.392 | 5 / 2 | 2.8 | Yes |
26795 | CHEMBL605866 | C10H12N6O4 | 280.244 | 8 / 4 | -1.5 | Yes |
27199 | CHEMBL2203713 | C18H22N4S | 326.462 | 4 / 2 | 2.9 | Yes |
27778 | CHEMBL561976 | C16H15BrClN5O3 | 440.682 | 7 / 3 | 2.0 | Yes |
28519 | MPC-MECA | C20H24N6O5 | 428.449 | 9 / 4 | 0.6 | Yes |
29532 | CHEMBL519319 | C17H15N5O5S2 | 433.457 | 7 / 0 | 1.4 | Yes |
32046 | CHEMBL608026 | C13H18N4O7 | 342.308 | 8 / 3 | -1.7 | Yes |
33925 | 205171-06-8 | C16H23N5O4 | 349.391 | 8 / 4 | 0.3 | Yes |
37149 | Kinetin riboside | C15H17N5O5 | 347.331 | 9 / 4 | 0.2 | Yes |
39607 | CHEMBL301574 | C12H17N5 | 231.303 | 4 / 1 | 1.7 | Yes |
40531 | CHEMBL2181972 | C12H14N6O4 | 306.282 | 9 / 4 | -0.3 | Yes |
42380 | CHEMBL610700 | C21H24N4O7 | 444.444 | 8 / 3 | 0.6 | Yes |
553453 | PSB 36 | C21H30N4O3 | 386.496 | 4 / 2 | 4.0 | Yes |
43247 | CHEMBL612203 | C30H40N8O6S | 640.76 | 12 / 5 | 2.6 | No |
43650 | MRE 3008-F20 | C21H20N8O3 | 432.444 | 7 / 2 | 2.5 | Yes |
44276 | CHEMBL606495 | C11H14ClN5O4 | 315.714 | 8 / 4 | 0.0 | Yes |
44498 | CHEMBL494086 | C16H16ClN5O2S | 377.847 | 7 / 3 | 1.7 | Yes |
45035 | CHEMBL609923 | C18H19ClN6O4 | 418.838 | 8 / 4 | 0.9 | Yes |
45651 | CHEMBL97778 | C15H11ClN2 | 254.717 | 2 / 0 | 4.1 | Yes |
46699 | CHEMBL111423 | C21H25NO3S | 371.495 | 5 / 0 | 5.2 | No |
48164 | 2'-Amino-2'-deoxyadenosine | C10H14N6O3 | 266.261 | 8 / 4 | -1.3 | Yes |
48679 | CHEMBL2113700 | C13H13IN6 | 380.193 | 5 / 2 | 2.2 | Yes |
48877 | CHEMBL374645 | C16H23N9O4 | 405.419 | 11 / 4 | -0.8 | No |
49629 | CHEMBL2113635 | C19H20FN7O5 | 445.411 | 9 / 5 | -0.2 | Yes |
52425 | CHEMBL94538 | C15H14N4 | 250.305 | 4 / 2 | 2.8 | Yes |
53533 | CHEMBL610112 | C23H25N9O8S | 587.568 | 13 / 6 | -0.6 | No |
54400 | CHEMBL16724 | C19H18N4O5 | 382.376 | 6 / 2 | 3.0 | Yes |
54815 | CHEMBL2113570 | C19H21N7O6 | 443.42 | 10 / 4 | 0.4 | Yes |
56160 | 3-DEAZAADENOSINE | C11H14N4O4 | 266.257 | 7 / 4 | -1.6 | Yes |
56804 | CHEMBL2113626 | C20H23N7O5 | 441.448 | 8 / 5 | 0.1 | Yes |
58231 | CHEMBL2051757 | C11H14N4O3 | 250.258 | 6 / 4 | -1.5 | Yes |
59359 | N6-aminoadenosine | C10H14N6O4 | 282.26 | 9 / 5 | -1.1 | Yes |
59762 | CHEMBL434328 | C27H26Cl2N6O4 | 569.443 | 8 / 4 | 3.5 | No |
60972 | CHEMBL92364 | C11H12N4O4 | 264.241 | 5 / 1 | -0.1 | Yes |
60984 | CHEMBL583745 | C29H35ClN8O4 | 595.101 | 9 / 6 | 0.8 | No |
523338 | CHEMBL3827201 | C29H42N6O3 | 522.694 | 6 / 0 | 5.0 | No |
61843 | CHEMBL1791403 | C11H15N5O4 | 281.272 | 8 / 4 | -0.6 | Yes |
61898 | CHEMBL610121 | C34H48N8O6S | 696.868 | 12 / 5 | 4.8 | No |
62341 | I-Abopx | C23H22IN5O5 | 575.363 | 7 / 3 | 4.4 | No |
62973 | CHEMBL112669 | C25H33N7O7 | 543.581 | 9 / 5 | -0.1 | No |
64571 | CHEMBL2113689 | C14H14IN5O | 395.204 | 5 / 2 | 2.2 | Yes |
64585 | CHEMBL423239 | C18H20N4O4 | 356.382 | 5 / 2 | 3.8 | Yes |
67382 | CHEMBL2113565 | C19H21ClN6O4 | 432.865 | 8 / 4 | 1.2 | Yes |
68904 | AC1LA9RB | C11H13ClN4O3 | 284.7 | 6 / 3 | 1.1 | Yes |
69730 | CHEMBL611863 | C22H36N4O6 | 452.552 | 7 / 3 | 2.6 | Yes |
69806 | CHEMBL2113613 | C19H21IN6O4 | 524.319 | 8 / 4 | 1.3 | No |
69924 | 8-Aminoadenosine | C10H14N6O4 | 282.26 | 9 / 5 | -1.4 | Yes |
71367 | CHEMBL609525 | C28H36N8O6S | 612.706 | 12 / 5 | 1.9 | No |
72121 | CHEMBL2113633 | C20H23N7O6 | 457.447 | 9 / 5 | -0.3 | Yes |
73230 | CHEMBL2322923 | C19H15N5O | 329.363 | 4 / 1 | 3.2 | Yes |
73363 | CHEMBL2113418 | C13H18N6O4 | 322.325 | 8 / 4 | -1.4 | Yes |
73384 | CHEMBL517867 | C21H14N4O2 | 354.369 | 4 / 1 | 4.1 | Yes |
74348 | CHEMBL202722 | C25H24N6O5 | 488.504 | 8 / 4 | 1.9 | Yes |
75509 | HE-NECA | C18H24N6O4 | 388.428 | 8 / 4 | 0.8 | Yes |
76489 | BDBM50059399 | C32H29NO4 | 491.587 | 5 / 0 | 6.1 | No |
76830 | 8-Cyclopentyl-1,3-dipropylxanthine | C16H24N4O2 | 304.394 | 3 / 1 | 4.0 | Yes |
77493 | CHEMBL3125714 | C20H25N5O2 | 367.453 | 6 / 3 | 2.4 | Yes |
79062 | CHEMBL2113696 | C18H19ClN6O2 | 386.84 | 6 / 2 | 2.6 | Yes |
79115 | CHEMBL327016 | C17H24N4O4 | 348.403 | 5 / 1 | 2.1 | Yes |
79291 | Xanthine amine congener | C21H28N6O4 | 428.493 | 6 / 3 | 2.7 | Yes |
79582 | CHEMBL416540 | C10H14N6O2 | 250.262 | 7 / 3 | -0.9 | Yes |
81037 | CHEMBL2113631 | C19H20ClN7O5 | 461.863 | 8 / 5 | 0.3 | Yes |
83542 | CHEMBL47437 | C16H17IN6O | 436.257 | 5 / 2 | 3.1 | Yes |
83651 | CHEMBL609240 | C19H29N5O6 | 423.47 | 7 / 3 | 0.5 | Yes |
83655 | CHEMBL138746 | C19H29N5O6 | 423.47 | 7 / 3 | 0.5 | Yes |
84353 | 2'-O-Methyladenosine | C11H15N5O4 | 281.272 | 8 / 3 | -0.5 | Yes |
88809 | CHEMBL2113637 | C19H20ClN7O5 | 461.863 | 8 / 5 | 0.3 | Yes |
88918 | CHEMBL415697 | C17H16N2O | 264.328 | 3 / 0 | 3.4 | Yes |
88986 | MSX-2 | C21H22N4O4 | 394.431 | 5 / 1 | 1.6 | Yes |
89533 | CHEMBL2113703 | C18H18ClIN6O3 | 528.735 | 7 / 3 | 2.3 | No |
91190 | CHEMBL444550 | C18H20IN5O4 | 497.293 | 8 / 4 | 1.1 | Yes |
91660 | CHEMBL193421 | C19H21N5O4 | 383.408 | 8 / 4 | 1.6 | Yes |
92064 | CHEMBL175543 | C20H20Cl2N6O3 | 463.319 | 7 / 4 | 2.0 | Yes |
95073 | CHEMBL344187 | C19H19IN6O4 | 522.303 | 8 / 4 | 0.3 | No |
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