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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL193421
Molecular formula	C19H21N5O4
IUPAC name	(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[(2-phenylcyclopropyl)amino]purin-9-yl]oxolane-3,4-diol
Molecular weight	383.408
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	1.6
Synonyms	BDBM50163010 (2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-(2-phenyl-cyclopropylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol
Inchi Key	GAIXIJBBHRACLL-UIKOTCIDSA-N
Inchi ID	InChI=1S/C19H21N5O4/c25-7-13-15(26)16(27)19(28-13)24-9-22-14-17(20-8-21-18(14)24)23-12-6-11(12)10-4-2-1-3-5-10/h1-5,8-9,11-13,15-16,19,25-27H,6-7H2,(H,20,21,23)/t11?,12?,13-,15-,16-,19-/m1/s1
PubChem CID	44401487
ChEMBL	CHEMBL193421
IUPHAR	N/A
BindingDB	50163010
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
91661	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
91666	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
91662	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
91663	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
91665	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
91660	Adenosine receptor A3	P28647	Adora3	Rattus norvegicus (Rat)	320
91664	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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