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| Name | Adenosine receptor A3 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | ADORA3 |
| Synonym | ARA3 Adenosine receptor A3 A3AR A3 receptor TGPCR1 |
| Disease | Cerebrovascular ischaemia Malaria Ischemia Inflammation Hepatocellular carcinoma; Hepatitis C virus infection [ Show all ] |
| Length | 318 |
| Amino acid sequence | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE |
| UniProt | P0DMS8 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | T36059 |
| ChEMBL | CHEMBL256 |
| IUPHAR | 21 |
| DrugBank | BE0000354 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 30 |  BDBM50059386 | C28H29NO4 | 443.543 | 5 / 0 | 5.0 | Yes |
| 441669 |  CHEMBL574416 | C17H12N4O | 288.31 | 3 / 1 | 2.7 | Yes |
| 441670 |  CHEMBL2113609 | C17H25N5O4 | 363.418 | 8 / 4 | 0.8 | Yes |
| 186 |  CHEMBL473650 | C21H14N6O2 | 382.383 | 5 / 1 | 2.8 | Yes |
| 441676 |  CHEMBL437168 | C26H26ClN7O6 | 567.987 | 10 / 5 | 2.2 | No |
| 364 |  CHEMBL573125 | C28H31ClN6O5 | 567.043 | 9 / 4 | 2.5 | No |
| 441686 |  diazepam | C16H13ClN2O | 284.743 | 2 / 0 | 3.0 | Yes |
| 480 |  CHEMBL38304 | C28H32N6O4 | 516.602 | 6 / 2 | 3.2 | No |
| 534 |  CHEMBL338501 | C21H14Cl2N4 | 393.271 | 3 / 1 | 5.0 | Yes |
| 441692 |  CHEMBL17202 | C28H29N5O4 | 499.571 | 5 / 2 | 5.5 | No |
| 613 |  CID 53633248 | C28H29N5O4 | 499.571 | 5 / 2 | 5.5 | No |
| 441693 |  CHEMBL323403 | C24H23NO3S | 405.512 | 5 / 0 | 5.9 | No |
| 671 |  CHEMBL343256 | C19H21N5O | 335.411 | 4 / 1 | 4.5 | Yes |
| 521466 |  CHEMBL3827623 | C26H36N6O3 | 480.613 | 6 / 0 | 3.9 | Yes |
| 441700 |  CHEMBL2170801 | C22H30ClN5O2 | 431.965 | 6 / 3 | 4.2 | Yes |
| 441701 |  CHEMBL468370 | C16H11N3O | 261.284 | 4 / 1 | 3.2 | Yes |
| 441702 |  CHEMBL2089347 | C27H24ClN5O2 | 485.972 | 6 / 3 | 4.2 | Yes |
| 441703 |  CHEMBL382194 | C18H20IN7O4 | 525.307 | 8 / 5 | 0.4 | No |
| 873 |  CHEMBL481383 | C20H23N5O2 | 365.437 | 3 / 0 | 3.6 | Yes |
| 900 |  CHEMBL72007 | C19H20N4O | 320.396 | 3 / 2 | 4.1 | Yes |
| 441705 |  2-amino-4-(1,3-benzodioxol-5-yl)-6-methoxypyridine-3,5-dicarbonitrile | C15H10N4O3 | 294.27 | 7 / 1 | 2.2 | Yes |
| 441709 |  CHEMBL1927632 | C8H7N7O | 217.192 | 7 / 2 | -0.1 | Yes |
| 441710 |  CHEMBL208311 | C25H30N6O4 | 478.553 | 8 / 4 | 2.7 | Yes |
| 1177 |  CHEMBL319971 | C17H14ClN5O2 | 355.782 | 5 / 1 | 3.2 | Yes |
| 441714 |  CHEMBL178846 | C22H25ClN6O5 | 488.929 | 9 / 4 | 1.3 | Yes |
| 1332 |  MRS-1042 | C24H28O5 | 396.483 | 5 / 0 | 6.0 | No |
| 441722 |  CHEMBL3121728 | C27H31ClN6O3 | 523.034 | 6 / 1 | 3.6 | No |
| 441723 |  CHEMBL1650163 | C18H13F2N3O | 325.319 | 5 / 1 | 3.2 | Yes |
| 441726 |  SCHEMBL1497826 | C22H20Cl3N3OS | 480.832 | 5 / 1 | 6.5 | No |
| 441728 |  hexachlorophene | C13H6Cl6O2 | 406.889 | 2 / 2 | 7.5 | No |
| 441732 |  CID 118733042 | C10H8N4OS | 232.261 | 4 / 1 | 1.1 | Yes |
| 441738 |  CHEMBL1094143 | C25H19N5O | 405.461 | 4 / 1 | 4.6 | Yes |
| 441739 |  CHEMBL603861 | C21H20F2N4O4 | 430.412 | 7 / 0 | 2.2 | Yes |
| 557349 |  CHEMBL124887 | C23H20N6O2 | 412.453 | 6 / 2 | 3.8 | Yes |
| 1991 |  CHEMBL515442 | C19H20ClIN6O5 | 574.76 | 9 / 4 | 1.7 | No |
| 441755 |  CHEMBL2112158 | C21H23ClN6O3 | 442.904 | 7 / 4 | 1.7 | Yes |
| 441760 |  CHEMBL434692 | C18H14BrNOS | 372.28 | 3 / 1 | 5.8 | No |
| 441761 |  CHEMBL259178 | C16H15N5O2 | 309.329 | 6 / 2 | 1.9 | Yes |
| 557361 |  CHEMBL2312720 | C18H13N3O3 | 319.32 | 4 / 1 | 2.9 | Yes |
| 441763 |  CHEMBL3410319 | C23H15F4N5O4 | 501.398 | 11 / 0 | 3.9 | No |
| 441766 |  CHEMBL218837 | C19H20ClN7O5 | 461.863 | 9 / 5 | 0.9 | Yes |
| 2319 |  CHEMBL366216 | C19H25N7 | 351.458 | 6 / 3 | 4.2 | Yes |
| 521524 |  CHEMBL3785142 | C14H17NO3S | 279.354 | 4 / 1 | 1.8 | Yes |
| 441842 |  CHEMBL3093226 | C21H27N5O3 | 397.479 | 5 / 0 | 2.7 | Yes |
| 441845 |  CHEMBL2113345 | C17H18N4O4 | 342.355 | 5 / 3 | 1.8 | Yes |
| 441847 |  CHEMBL1927430 | C19H28N8O5 | 448.484 | 11 / 3 | 1.0 | No |
| 3623 |  CHEMBL574502 | C23H22ClN7O3 | 479.925 | 7 / 1 | 4.3 | Yes |
| 3675 |  CHEMBL490250 | C17H22ClN5O4 | 395.844 | 8 / 4 | 2.3 | Yes |
| 441858 |  CHEMBL186443 | C19H20N8O4 | 424.421 | 10 / 4 | -0.4 | Yes |
| 3816 |  CHEMBL257256 | C16H18ClN3O2S | 351.849 | 5 / 1 | 3.9 | Yes |
| 557392 |  CHEMBL124724 | C18H20N6 | 320.4 | 4 / 1 | 4.3 | Yes |
| 441860 |  CEP-11981 | C28H27N7O | 477.572 | 5 / 2 | 3.9 | Yes |
| 3854 |  316173-57-6 | C20H19N7O2 | 389.419 | 7 / 1 | 2.7 | Yes |
| 557394 |  CHEMBL123144 | C16H15BrN6 | 371.242 | 4 / 1 | 4.1 | Yes |
| 441862 |  CHEMBL2391832 | C20H13N3O3S | 375.402 | 6 / 1 | 3.8 | Yes |
| 4043 |  CHEMBL428716 | C22H29N7O6 | 487.517 | 11 / 4 | 1.1 | No |
| 441877 |  CHEMBL235717 | C24H18ClN5O3 | 459.89 | 5 / 1 | 5.7 | No |
| 441878 |  CHEMBL465640 | C17H11F3N4 | 328.298 | 6 / 1 | 4.0 | Yes |
| 4208 |  CHEMBL278805 | C22H22Cl2N8O3S | 549.431 | 9 / 1 | 2.7 | No |
| 441881 |  CHEMBL446264 | C8H10BrN5 | 256.107 | 4 / 1 | 1.4 | Yes |
| 459258 |  BDBM50052395 | C14H21NO5 | 283.324 | 6 / 0 | 0.8 | Yes |
| 441882 |  sulconazole | C18H15Cl3N2S | 397.742 | 2 / 0 | 6.1 | No |
| 4331 |  CHEMBL123669 | C20H19ClN4O | 366.849 | 4 / 0 | 5.4 | No |
| 4352 |  CHEMBL574701 | C21H17N7O5 | 447.411 | 10 / 2 | 2.2 | Yes |
| 4355 |  CHEMBL22355 | C21H17N7O5 | 447.411 | 10 / 2 | 2.2 | Yes |
| 441883 |  CHEMBL3087709 | C23H17N5O2 | 395.422 | 5 / 1 | 3.6 | Yes |
| 4436 |  CHEMBL574490 | C19H13Cl2N7O2 | 442.26 | 6 / 1 | 3.2 | Yes |
| 4511 |  CHEMBL575605 | C31H25N7O2 | 527.588 | 6 / 1 | 5.4 | No |
| 441889 |  CHEMBL3125715 | C22H29N5O2 | 395.507 | 6 / 3 | 3.1 | Yes |
| 441890 |  120-78-5 | C14H8N2S4 | 332.472 | 6 / 0 | 5.6 | No |
| 521591 |  871266-83-0 | C11H6ClN5O2S | 307.712 | 7 / 1 | 3.7 | Yes |
| 4751 |  CHEMBL27376 | C20H20ClIN6O3 | 554.773 | 7 / 4 | 2.0 | No |
| 441892 |  CHEMBL133387 | C20H20ClIN6O3 | 554.773 | 7 / 4 | 2.0 | No |
| 441893 |  CHEMBL376778 | C20H19N3O | 317.392 | 3 / 1 | 4.1 | Yes |
| 441894 |  CHEMBL1171381 | C31H37N5O4 | 543.668 | 5 / 0 | 4.4 | No |
| 441896 |  CHEMBL611552 | C20H22N10O7 | 514.459 | 14 / 5 | -0.1 | No |
| 441897 |  CHEMBL2413111 | C20H22N10O7 | 514.459 | 14 / 5 | -0.1 | No |
| 459262 |  CHEMBL611552 | C20H22N10O7 | 514.459 | 14 / 5 | -0.1 | No |
| 441898 |  CHEMBL1258192 | C22H23N7O2 | 417.473 | 7 / 1 | 3.5 | Yes |
| 441899 |  CHEMBL2203622 | C18H22N2O2 | 298.386 | 3 / 0 | 3.8 | Yes |
| 441900 |  CHEMBL2042308 | C49H58N8O5 | 839.054 | 10 / 6 | 9.0 | No |
| 441902 |  CHEMBL1766351 | C21H15ClN4O2 | 390.827 | 3 / 2 | 4.1 | Yes |
| 5039 |  CHEMBL179315 | C28H30N8O4 | 542.6 | 8 / 2 | 4.2 | No |
| 441911 |  CHEMBL3415043 | C13H12N4O2S | 288.325 | 6 / 2 | 2.2 | Yes |
| 5268 |  CHEMBL164039 | C24H29NO4S2 | 459.619 | 7 / 0 | 5.6 | No |
| 463518 |  CHEMBL3612943 | C20H20ClN9O3S | 501.95 | 10 / 4 | 1.0 | No |
| 441913 |  CHEMBL3093315 | C17H17N5O2S | 355.416 | 5 / 0 | 1.4 | Yes |
| 5611 |  UNII-29S2U9DRGS | C27H28N6O5 | 516.558 | 8 / 1 | 5.7 | No |
| 441918 |  CHEMBL589513 | C43H56ClN11O7S | 906.501 | 12 / 9 | 1.2 | No |
| 5628 |  CHEMBL583748 | C43H56ClN11O7S | 906.501 | 12 / 9 | 1.2 | No |
| 441919 |  2-(1-hexynyl)adenosine | C16H21N5O4 | 347.375 | 8 / 4 | 1.3 | Yes |
| 5738 |  CHEMBL107637 | C17H14N4 | 274.327 | 3 / 1 | 3.5 | Yes |
| 521632 |  CHEMBL3828530 | C20H26N6O3 | 398.467 | 6 / 0 | 1.7 | Yes |
| 5869 |  CHEMBL72287 | C22H16N2O | 324.383 | 3 / 0 | 4.0 | Yes |
| 5904 |  CHEMBL574352 | C13H12N4O | 240.266 | 3 / 1 | 1.4 | Yes |
| 441922 |  CHEMBL220386 | C21H21FN6O5 | 456.434 | 10 / 4 | 1.3 | Yes |
| 441939 |  CHEMBL208530 | C12H17N7O4 | 323.313 | 8 / 5 | -1.0 | Yes |
| 441944 |  CHEMBL3314874 | C27H26N6O4 | 498.543 | 8 / 2 | 3.8 | Yes |
| 441948 |  CHEMBL3410309 | C19H21N5O3 | 367.409 | 6 / 1 | 3.0 | Yes |
| 6505 |  CHEMBL142926 | C23H22N8O3 | 458.482 | 7 / 2 | 3.3 | Yes |
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