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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL366216
Molecular formula	C19H25N7
IUPAC name	6-N-cyclohexyl-2-N-[4-(dimethylamino)phenyl]-7H-purine-2,6-diamine
Molecular weight	351.458
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	4.2
Synonyms	BDBM50170823 N6-Cyclohexyl-N2-(4-dimethylamino-phenyl)-9H-purine-2,6-diamine
Inchi Key	ADHPIOBOQMGIPQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H25N7/c1-26(2)15-10-8-14(9-11-15)23-19-24-17-16(20-12-21-17)18(25-19)22-13-6-4-3-5-7-13/h8-13H,3-7H2,1-2H3,(H3,20,21,22,23,24,25)
PubChem CID	11302588
ChEMBL	CHEMBL366216
IUPHAR	N/A
BindingDB	50170823
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2318	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
2317	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
2319	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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