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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-amino-4-(1,3-benzodioxol-5-yl)-6-methoxypyridine-3,5-dicarbonitrile
Molecular formula	C15H10N4O3
IUPAC name	2-amino-4-(1,3-benzodioxol-5-yl)-6-methoxypyridine-3,5-dicarbonitrile
Molecular weight	294.27
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.2
Synonyms	CHEMBL142641 ZINC19300843 4-Aryl-2-aminopyridine deriv. 10 AKOS001610557 MolPort-001-897-102 Cambridge id 5136030 ST50911758 4-(1,3-Benzodioxole-5-yl)-2-methoxy-6-aminopyridine-3,5-dicarbonitrile EU-0035166 BAS 00381296 SR-01000403124 2-amino-4-(2H-1,3-benzodioxol-5-yl)-6-methoxypyridine-3,5-dicarbonitrile STK384975 4-(2H-benzo[d]1,3-dioxolen-5-yl)-2-amino-6-methoxypyridine-3,5-dicarbonitrile AC1LDSV7 MCULE-3886974351 BDBM6643 SR-01000403124-1 2-Amino-4-benzo[1,3]dioxol-5-yl-6-methoxy-pyridine-3,5-dicarbonitrile [ Show all ]
Inchi Key	ABLFQJZRWXQNFZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H10N4O3/c1-20-15-10(6-17)13(9(5-16)14(18)19-15)8-2-3-11-12(4-8)22-7-21-11/h2-4H,7H2,1H3,(H2,18,19)
PubChem CID	700373
ChEMBL	CHEMBL142641
IUPHAR	N/A
BindingDB	6643
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
936	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
935	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
937	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
441705	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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