You can:
| Name | Adenosine receptor A2b |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | ADORA2B |
| Synonym | adenosine receptor A2b A2BR A2B receptor A2b |
| Disease | Paroxysmal supraventricular tachycardia Non-insulin dependent diabetes Hypertension Herpes simplex virus infection Apnea [ Show all ] |
| Length | 332 |
| Amino acid sequence | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL |
| UniProt | P29275 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P29275 |
| 3D structure model | This predicted structure model is from GPCR-EXP P29275. |
| BioLiP | N/A |
| Therapeutic Target Database | T86679 |
| ChEMBL | CHEMBL255 |
| IUPHAR | 20 |
| DrugBank | BE0000241 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 46 |  CHEMBL574416 | C17H12N4O | 288.31 | 3 / 1 | 2.7 | Yes |
| 233 |  CHEMBL201449 | C26H26N4O7 | 506.515 | 7 / 2 | 2.7 | No |
| 237 |  CHEMBL437168 | C26H26ClN7O6 | 567.987 | 10 / 5 | 2.2 | No |
| 477 |  CHEMBL38304 | C28H32N6O4 | 516.602 | 6 / 2 | 3.2 | No |
| 608 |  CHEMBL17202 | C28H29N5O4 | 499.571 | 5 / 2 | 5.5 | No |
| 611 |  CID 53633248 | C28H29N5O4 | 499.571 | 5 / 2 | 5.5 | No |
| 688 |  CHEMBL196259 | C16H16N8 | 320.36 | 6 / 1 | 2.3 | Yes |
| 521463 |  CHEMBL3827623 | C26H36N6O3 | 480.613 | 6 / 0 | 3.9 | Yes |
| 801 |  CHEMBL468370 | C16H11N3O | 261.284 | 4 / 1 | 3.2 | Yes |
| 870 |  CHEMBL481383 | C20H23N5O2 | 365.437 | 3 / 0 | 3.6 | Yes |
| 895 |  CHEMBL561167 | C18H22N4O3 | 342.399 | 4 / 1 | 3.3 | Yes |
| 937 |  2-amino-4-(1,3-benzodioxol-5-yl)-6-methoxypyridine-3,5-dicarbonitrile | C15H10N4O3 | 294.27 | 7 / 1 | 2.2 | Yes |
| 992 |  CHEMBL1927632 | C8H7N7O | 217.192 | 7 / 2 | -0.1 | Yes |
| 999 |  CHEMBL208311 | C25H30N6O4 | 478.553 | 8 / 4 | 2.7 | Yes |
| 1175 |  CHEMBL319971 | C17H14ClN5O2 | 355.782 | 5 / 1 | 3.2 | Yes |
| 1204 |  CHEMBL178846 | C22H25ClN6O5 | 488.929 | 9 / 4 | 1.3 | Yes |
| 1410 |  CHEMBL181062 | C26H25ClN6O4 | 520.974 | 7 / 1 | 6.3 | No |
| 1422 |  8-Phenylxanthine | C11H8N4O2 | 228.211 | 3 / 3 | 0.9 | Yes |
| 1450 |  CHEMBL3121728 | C27H31ClN6O3 | 523.034 | 6 / 1 | 3.6 | No |
| 1479 |  CHEMBL1650163 | C18H13F2N3O | 325.319 | 5 / 1 | 3.2 | Yes |
| 441731 |  CID 118733042 | C10H8N4OS | 232.261 | 4 / 1 | 1.1 | Yes |
| 1716 |  CHEMBL1094143 | C25H19N5O | 405.461 | 4 / 1 | 4.6 | Yes |
| 1815 |  CHEMBL603861 | C21H20F2N4O4 | 430.412 | 7 / 0 | 2.2 | Yes |
| 2057 |  CHEMBL407372 | C28H25F6N5O4 | 609.529 | 11 / 1 | 4.9 | No |
| 2122 |  CHEMBL2112158 | C21H23ClN6O3 | 442.904 | 7 / 4 | 1.7 | Yes |
| 2242 |  CHEMBL259178 | C16H15N5O2 | 309.329 | 6 / 2 | 1.9 | Yes |
| 557359 |  CHEMBL2312720 | C18H13N3O3 | 319.32 | 4 / 1 | 2.9 | Yes |
| 441762 |  CHEMBL3410319 | C23H15F4N5O4 | 501.398 | 11 / 0 | 3.9 | No |
| 2310 |  CHEMBL218837 | C19H20ClN7O5 | 461.863 | 9 / 5 | 0.9 | Yes |
| 521527 |  CHEMBL3785142 | C14H17NO3S | 279.354 | 4 / 1 | 1.8 | Yes |
| 3184 |  CHEMBL201847 | C26H28N4O4 | 460.534 | 4 / 1 | 3.5 | Yes |
| 3324 |  CHEMBL3093226 | C21H27N5O3 | 397.479 | 5 / 0 | 2.7 | Yes |
| 3432 |  CHEMBL2113345 | C17H18N4O4 | 342.355 | 5 / 3 | 1.8 | Yes |
| 3619 |  CHEMBL1927430 | C19H28N8O5 | 448.484 | 11 / 3 | 1.0 | No |
| 3676 |  CHEMBL490250 | C17H22ClN5O4 | 395.844 | 8 / 4 | 2.3 | Yes |
| 3856 |  316173-57-6 | C20H19N7O2 | 389.419 | 7 / 1 | 2.7 | Yes |
| 3958 |  CHEMBL2391832 | C20H13N3O3S | 375.402 | 6 / 1 | 3.8 | Yes |
| 4040 |  CHEMBL428716 | C22H29N7O6 | 487.517 | 11 / 4 | 1.1 | No |
| 517336 |  SCHEMBL246621 | C29H29N5O3S | 527.643 | 8 / 2 | 4.1 | No |
| 4086 |  CHEMBL235717 | C24H18ClN5O3 | 459.89 | 5 / 1 | 5.7 | No |
| 4119 |  CHEMBL465640 | C17H11F3N4 | 328.298 | 6 / 1 | 4.0 | Yes |
| 4123 |  BDBM85526 | C18H22IN7O4 | 527.323 | 10 / 6 | 1.2 | No |
| 4165 |  CHEMBL457014 | C18H20N4O5 | 372.381 | 5 / 2 | 2.9 | Yes |
| 4210 |  CHEMBL278805 | C22H22Cl2N8O3S | 549.431 | 9 / 1 | 2.7 | No |
| 4240 |  CHEMBL446264 | C8H10BrN5 | 256.107 | 4 / 1 | 1.4 | Yes |
| 4356 |  CHEMBL22355 | C21H17N7O5 | 447.411 | 10 / 2 | 2.2 | Yes |
| 4385 |  CHEMBL3087709 | C23H17N5O2 | 395.422 | 5 / 1 | 3.6 | Yes |
| 4439 |  CHEMBL574490 | C19H13Cl2N7O2 | 442.26 | 6 / 1 | 3.2 | Yes |
| 4513 |  CHEMBL575605 | C31H25N7O2 | 527.588 | 6 / 1 | 5.4 | No |
| 521593 |  871266-83-0 | C11H6ClN5O2S | 307.712 | 7 / 1 | 3.7 | Yes |
| 4756 |  CHEMBL27376 | C20H20ClIN6O3 | 554.773 | 7 / 4 | 2.0 | No |
| 4760 |  CHEMBL376778 | C20H19N3O | 317.392 | 3 / 1 | 4.1 | Yes |
| 4818 |  CHEMBL1171381 | C31H37N5O4 | 543.668 | 5 / 0 | 4.4 | No |
| 4995 |  CHEMBL2042308 | C49H58N8O5 | 839.054 | 10 / 6 | 9.0 | No |
| 441909 |  CHEMBL3415043 | C13H12N4O2S | 288.325 | 6 / 2 | 2.2 | Yes |
| 5370 |  CHEMBL3093315 | C17H17N5O2S | 355.416 | 5 / 0 | 1.4 | Yes |
| 5401 |  CHEMBL370588 | C23H21BrN4O4 | 497.349 | 4 / 2 | 3.6 | Yes |
| 5609 |  UNII-29S2U9DRGS | C27H28N6O5 | 516.558 | 8 / 1 | 5.7 | No |
| 5632 |  2-(1-hexynyl)adenosine | C16H21N5O4 | 347.375 | 8 / 4 | 1.3 | Yes |
| 5842 |  CHEMBL201611 | C26H29N5O4 | 475.549 | 5 / 2 | 3.9 | Yes |
| 521633 |  CHEMBL3828530 | C20H26N6O3 | 398.467 | 6 / 0 | 1.7 | Yes |
| 5907 |  CHEMBL574352 | C13H12N4O | 240.266 | 3 / 1 | 1.4 | Yes |
| 441943 |  CHEMBL3314874 | C27H26N6O4 | 498.543 | 8 / 2 | 3.8 | Yes |
| 441947 |  CHEMBL3410309 | C19H21N5O3 | 367.409 | 6 / 1 | 3.0 | Yes |
| 6503 |  CHEMBL142926 | C23H22N8O3 | 458.482 | 7 / 2 | 3.3 | Yes |
| 6540 |  CHEMBL1092868 | C16H13N7O2S | 367.387 | 7 / 2 | 2.4 | Yes |
| 6552 |  CHEMBL259479 | C31H33ClN6O4S | 621.153 | 7 / 1 | 5.6 | No |
| 463671 |  CHEMBL3581311 | C19H26N10O | 410.486 | 7 / 2 | 1.1 | Yes |
| 6732 |  MRS 1754 | C26H26N6O4 | 486.532 | 6 / 2 | 4.9 | Yes |
| 6739 |  CHEMBL1628266 | C26H26N6O4 | 506.612 | 6 / 2 | 4.9 | No |
| 6962 |  CHEMBL179935 | C26H25ClN6O4 | 520.974 | 7 / 1 | 6.2 | No |
| 6969 |  CHEMBL2070887 | C24H24FN9O2 | 489.515 | 8 / 2 | 2.4 | Yes |
| 7067 |  CHEMBL3091701 | C13H16N2O3S | 280.342 | 4 / 2 | 1.5 | Yes |
| 7095 |  CHEMBL1650169 | C22H23N3O5 | 409.442 | 7 / 1 | 2.9 | Yes |
| 7281 |  CHEMBL201496 | C25H23N5O4 | 457.49 | 5 / 2 | 2.9 | Yes |
| 7292 |  CID 71508724 | C15H23N7O8 | 429.39 | 14 / 9 | -2.7 | No |
| 7388 |  CHEMBL1650167 | C21H21N3O3 | 363.417 | 5 / 1 | 3.4 | Yes |
| 7399 |  CHEMBL1650353 | C21H15F6N3O | 439.361 | 9 / 1 | 5.3 | No |
| 7945 |  CHEMBL562427 | C25H27N5O6 | 493.52 | 7 / 3 | 3.3 | Yes |
| 536175 |  CHEMBL3980193 | C29H29Cl2N7O3 | 594.497 | 6 / 3 | 3.7 | No |
| 8046 |  CHEMBL561364 | C27H29N5O6 | 519.558 | 7 / 2 | 3.3 | No |
| 8395 |  BDBM50166741 | C13H7N6O2S- | 311.299 | 7 / 1 | 2.6 | Yes |
| 8399 |  CHEMBL1161797 | C13H8N6O2S | 312.307 | 7 / 2 | 2.0 | Yes |
| 8505 |  CHEMBL2180915 | C17H21N7O2 | 355.402 | 7 / 2 | 1.9 | Yes |
| 8799 |  CHEMBL499220 | C17H13N3O | 275.311 | 4 / 1 | 3.5 | Yes |
| 8977 |  CHEMBL460805 | C20H21N7O2 | 391.435 | 7 / 1 | 2.0 | Yes |
| 9043 |  CHEMBL2042067 | C12H11BrN2O3 | 311.135 | 4 / 3 | 1.5 | Yes |
| 9284 |  446252-18-2 | C13H16N2O4 | 264.281 | 4 / 2 | 0.9 | Yes |
| 9295 |  N-(2-hydroxyethyl)-8-methoxy-2-oxo-2H-chromene-3-carboxamide | C13H13NO5 | 263.249 | 5 / 2 | 1.2 | Yes |
| 557538 |  CHEMBL1800784 | C17H21N7O2 | 355.402 | 5 / 1 | 1.4 | Yes |
| 557539 |  CHEMBL1800783 | C17H21N7O2 | 355.402 | 5 / 1 | 1.4 | Yes |
| 557545 |  CHEMBL1800782 | C17H21N7O2 | 355.402 | 5 / 1 | 1.4 | Yes |
| 9812 |  CHEMBL32507 | C23H24IN7O4 | 589.394 | 7 / 2 | 2.9 | No |
| 442106 |  CHEMBL3410310 | C20H22FN5O3 | 399.426 | 7 / 1 | 3.7 | Yes |
| 10498 |  CHEMBL2070882 | C20H25N9O2 | 423.481 | 7 / 2 | 1.7 | Yes |
| 10644 |  CHEMBL1834695 | C22H17F3N8O2 | 482.427 | 9 / 2 | 3.5 | Yes |
| 10662 |  CHEMBL518497 | C16H14N6O2 | 322.328 | 7 / 1 | 1.7 | Yes |
| 10665 |  CHEMBL444281 | C25H27N5O5 | 477.521 | 6 / 3 | 4.8 | Yes |
| 10672 |  CHEMBL2391843 | C22H21N7OS | 431.518 | 8 / 2 | 4.0 | Yes |
| 10793 |  CHEMBL201502 | C26H27FN4O5 | 494.523 | 6 / 3 | 4.0 | Yes |
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