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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL407372
Molecular formula	C28H25F6N5O4
IUPAC name	6-[4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-1,3-bis(2,2,2-trifluoroethyl)-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Molecular weight	609.529
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	4.9
Synonyms	N/A
Inchi Key	ACZPVONLWCNWJJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H25F6N5O4/c29-27(30,31)16-38-22-14-21(35-24(22)25(41)39(26(38)42)17-28(32,33)34)18-6-8-20(9-7-18)43-15-23(40)37-12-10-36(11-13-37)19-4-2-1-3-5-19/h1-9,14,35H,10-13,15-17H2
PubChem CID	44451000
ChEMBL	CHEMBL407372
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2058	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
2057	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332

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