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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL574490
Molecular formula	C19H13Cl2N7O2
IUPAC name	2-(2,6-dichlorophenyl)-N-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]acetamide
Molecular weight	442.26
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.2
Synonyms	BDBM50298517 5-[(2,6-Dichlorobenzyl)carbonyl]amino-8-methyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine(
Inchi Key	AFSNHUCXKASIMR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H13Cl2N7O2/c1-27-9-11-16(25-27)24-19(22-15(29)8-10-12(20)4-2-5-13(10)21)28-18(11)23-17(26-28)14-6-3-7-30-14/h2-7,9H,8H2,1H3,(H,22,24,25,29)
PubChem CID	45482087
ChEMBL	CHEMBL574490
IUPHAR	N/A
BindingDB	50298517
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
4437	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
4438	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
4439	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
4436	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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