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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	8-Phenylxanthine
Molecular formula	C11H8N4O2
IUPAC name	8-phenyl-3,7-dihydropurine-2,6-dione
Molecular weight	228.211
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	0.9
Synonyms	1H-Purine-2,6-dione, 3,9-dihydro-8-phenyl- ZINC13472986 D0L8DZ 0S2BVG6C31 UNII-0S2BVG6C31 2879-14-3 CHEMBL285191 8-Phenyl-1H-purine-2,6(3H,7H)-dione DTXSID50485464 1H-Purine-2,6-dione, 3,7-dihydro-8-phenyl- BDBM50042214 Xanthine, 8-phenyl- 3,7-Dihydro-8-phenyl-1H-purine-2,6-dione CTK0J1822 8-Phenyl-3,7-dihydro-purine-2,6-dione SCHEMBL378879 [ Show all ]
Inchi Key	ACCCXSZCOGNLFL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H8N4O2/c16-10-7-9(14-11(17)15-10)13-8(12-7)6-4-2-1-3-5-6/h1-5H,(H3,12,13,14,15,16,17)
PubChem CID	12295530
ChEMBL	CHEMBL285191
IUPHAR	N/A
BindingDB	50042214
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1420	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
1421	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
1422	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332

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