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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A3
Species	Rattus norvegicus (Rat)
Gene	Adora3
Synonym	A3 receptor A3AR Adenosine receptor A3 ARA3 TGPCR1
Disease	N/A for non-human GPCRs
Length	320
Amino acid sequence	MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
UniProt	P28647
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3360
IUPHAR	21
DrugBank	N/A

Ligand

Name	CHEMBL97778
Molecular formula	C15H11ClN2
IUPAC name	4-chloro-7-methyl-2-phenyl-1,8-naphthyridine
Molecular weight	254.717
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.1
Synonyms	BDBM50090689 D09KUY 4-Chloro-7-methyl-2-phenyl-[1,8]naphthyridine 2-Phenyl-4-chloro-7-methyl-1,8-naphthyridine SCHEMBL1536334 4-chloro-7-methyl-2-phenyl-1,8-naphthyridine ZINC13579501 [ Show all ]
Inchi Key	CMSOCFLZPHQUAD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H11ClN2/c1-10-7-8-12-13(16)9-14(18-15(12)17-10)11-5-3-2-4-6-11/h2-9H,1H3
PubChem CID	12431921
ChEMBL	CHEMBL97778
IUPHAR	N/A
BindingDB	50090689
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	<10000.0 nM	PMID10956189	BindingDB,ChEMBL

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