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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A3
Species	Rattus norvegicus (Rat)
Gene	Adora3
Synonym	A3 receptor A3AR Adenosine receptor A3 ARA3 TGPCR1
Disease	N/A for non-human GPCRs
Length	320
Amino acid sequence	MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
UniProt	P28647
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3360
IUPHAR	21
DrugBank	N/A

Ligand

Name	CHEMBL2113685
Molecular formula	C16H18IN5O2S
IUPAC name	(2S)-3-[6-[(3-iodophenyl)methylamino]-2-methylsulfanylpurin-9-yl]propane-1,2-diol
Molecular weight	471.317
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	2.0
Synonyms	BDBM50453666
Inchi Key	AQADPXZMOSNTQN-LBPRGKRZSA-N
Inchi ID	InChI=1S/C16H18IN5O2S/c1-25-16-20-14(18-6-10-3-2-4-11(17)5-10)13-15(21-16)22(9-19-13)7-12(24)8-23/h2-5,9,12,23-24H,6-8H2,1H3,(H,18,20,21)/t12-/m0/s1
PubChem CID	71459963
ChEMBL	CHEMBL2113685
IUPHAR	N/A
BindingDB	50453666
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Effect	0.0 -	PMID7752196	ChEMBL
Inhibition	5.5 %	PMID7752196	ChEMBL
Inhibition	7.3 %	PMID7752196	ChEMBL
Ki	8590.0 nM	PMID7752196	BindingDB,ChEMBL
Ratio	4.6 -	PMID7752196	ChEMBL

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