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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2051757
Molecular formula	C11H14N4O3
IUPAC name	(1R,2S,3R,4S)-4-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2,3-triol
Molecular weight	250.258
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-1.5
Synonyms	(+)-7-Deaza-5'-noraristeromycin AC1NRPSV (1R,2S,3R,4S)-4-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2,3-triol BDBM50408389 1,2,3-Cyclopentanetriol, 4-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-, (1R,2S,3R,4S)-
Inchi Key	DEXGSOQQTISOEO-KDXUFGMBSA-N
Inchi ID	InChI=1S/C11H14N4O3/c12-10-5-1-2-15(11(5)14-4-13-10)6-3-7(16)9(18)8(6)17/h1-2,4,6-9,16-18H,3H2,(H2,12,13,14)/t6-,7+,8+,9-/m0/s1
PubChem CID	5270728
ChEMBL	CHEMBL2051757
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
443989	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
443990	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
58231	Adenosine receptor A3	P28647	Adora3	Rattus norvegicus (Rat)	320

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