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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A3
Species	Rattus norvegicus (Rat)
Gene	Adora3
Synonym	A3 receptor A3AR Adenosine receptor A3 ARA3 TGPCR1
Disease	N/A for non-human GPCRs
Length	320
Amino acid sequence	MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
UniProt	P28647
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3360
IUPHAR	21
DrugBank	N/A

Ligand

Name	CHEMBL112669
Molecular formula	C25H33N7O7
IUPAC name	2-[[2-[2-[[2-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenoxy]acetyl]amino]ethylamino]-2-oxoethyl]amino]acetic acid
Molecular weight	543.581
Hydrogen bond acceptor	9
Hydrogen bond donor	5
XlogP	-0.1
Synonyms	{[(2-{2-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenoxy]-acetylamino}-ethylcarbamoyl)-methyl]-amino}-acetic acid BDBM50037438 [[2-[[2-[[2-[4-[(1,3-Dipropyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin)-8-yl]phenoxy]acetyl]amino]ethyl]amino]-2-oxoethyl]amino]acetic acid
Inchi Key	DLIFOYBZSVXZFZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H33N7O7/c1-3-11-31-23-21(24(37)32(12-4-2)25(31)38)29-22(30-23)16-5-7-17(8-6-16)39-15-19(34)28-10-9-27-18(33)13-26-14-20(35)36/h5-8,26H,3-4,9-15H2,1-2H3,(H,27,33)(H,28,34)(H,29,30)(H,35,36)
PubChem CID	10392599
ChEMBL	CHEMBL112669
IUPHAR	N/A
BindingDB	50037438
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Ki	98000.0 nM	PMID7932565	BindingDB,ChEMBL

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