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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	8-Aminoadenosine
Molecular formula	C10H14N6O4
IUPAC name	(2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Molecular weight	282.26
Hydrogen bond acceptor	9
Hydrogen bond donor	5
XlogP	-1.4
Synonyms	3BH adenosine-derived inhibitor, 4 KB-46628 9H-Purine, 6,8-diamino-9-beta-D-ribofuranosyl- C-52921 SCHEMBL1145049 Adenosine, 8-amino- CTK1C3435 AKOS027430455 NCGC00485421-01 (2R,3R,4S,5R)-2-(6,8-diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol AC1L3XCX Z6050 3868-33-5 adenosine-derived inhibitor (Grp78), 2 FT-0658744 8-Amionadenosine BDBM32370 NSC 90394 (2R,3R,4S,5R)-2-(6,8-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol AC1Q4Y4N CHEMBL516197 ZINC5163030 [ Show all ]
Inchi Key	DVGWFQILDUEEGX-UUOKFMHZSA-N
Inchi ID	InChI=1S/C10H14N6O4/c11-7-4-8(14-2-13-7)16(10(12)15-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,15)(H2,11,13,14)/t3-,5-,6-,9-/m1/s1
PubChem CID	96851
ChEMBL	CHEMBL516197
IUPHAR	N/A
BindingDB	32370
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
69926	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
69925	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
69924	Adenosine receptor A3	P28647	Adora3	Rattus norvegicus (Rat)	320

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