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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A3
Species	Rattus norvegicus (Rat)
Gene	Adora3
Synonym	A3 receptor A3AR Adenosine receptor A3 ARA3 TGPCR1
Disease	N/A for non-human GPCRs
Length	320
Amino acid sequence	MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
UniProt	P28647
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3360
IUPHAR	21
DrugBank	N/A

Ligand

Name	CHEMBL202722
Molecular formula	C25H24N6O5
IUPAC name	(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-[(4-phenylbenzoyl)amino]purin-9-yl]oxolane-2-carboxamide
Molecular weight	488.504
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	1.9
Synonyms	BDBM50179025 N-[(1,1'-Biphenyl-4-yl)carbonyl]-5'-(ethylamino)-5'-oxo-5'-deoxyadenosine (2S,3S,4R,5R)-5-{6-[(Biphenyl-4-carbonyl)-amino]-purin-9-yl}-3,4-dihydroxy-tetrahydro-furan-2-carboxylicacid ethylamide
Inchi Key	FBMOMQNCWCOOAE-PBQROFAYSA-N
Inchi ID	InChI=1S/C25H24N6O5/c1-2-26-24(35)20-18(32)19(33)25(36-20)31-13-29-17-21(27-12-28-22(17)31)30-23(34)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-13,18-20,25,32-33H,2H2,1H3,(H,26,35)(H,27,28,30,34)/t18-,19+,20-,25+/m0/s1
PubChem CID	10529007
ChEMBL	CHEMBL202722
IUPHAR	N/A
BindingDB	50179025
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	979.0 nM	PMID9703463, PMID15990306, PMID16356715	BindingDB,ChEMBL

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