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| Name | C-X-C chemokine receptor type 1 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | CXCR1 |
| Synonym | CDw128a IL8RA IL-8R A IL-8 receptor type I IL-8 receptor type 1 [ Show all ] |
| Disease | N/A |
| Length | 350 |
| Amino acid sequence | MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL |
| UniProt | P25024 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P25024 |
| 3D structure model | This predicted structure model is from GPCR-EXP P25024. |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4029 |
| IUPHAR | 68 |
| DrugBank | BE0003552 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 2034 |  CHEMBL216602 | C20H21N3O5 | 383.404 | 7 / 3 | 2.6 | Yes |
| 441843 |  CHEMBL3426944 | C20H15BF4N2O4S | 466.214 | 10 / 3 | N/A | N/A |
| 463342 |  CHEMBL3704558 | C25H25N3O7 | 479.489 | 9 / 3 | 2.8 | Yes |
| 463403 |  CHEMBL3704567 | C19H18ClN3O5 | 403.819 | 7 / 3 | 2.2 | Yes |
| 533925 |  CHEMBL3976863 | C29H32FN3O6S | 569.648 | 10 / 2 | 4.6 | No |
| 536267 |  SCHEMBL1198501 | C18H16ClF2N3O6S | 475.848 | 9 / 4 | 2.9 | Yes |
| 12655 |  CHEMBL220182 | C23H23N3O6 | 437.452 | 8 / 3 | 3.4 | Yes |
| 12681 |  CHEMBL26830 | C14H9BrClN3O2 | 366.599 | 3 / 3 | 3.7 | Yes |
| 13449 |  CHEMBL250689 | C28H36FN3O2 | 465.613 | 4 / 2 | 5.2 | No |
| 464521 |  CHEMBL3609011 | C19H18BFN4O3 | 380.186 | 7 / 3 | N/A | N/A |
| 536412 |  SCHEMBL1199104 | C17H18Cl2N4O4S | 445.315 | 6 / 4 | 2.6 | Yes |
| 16837 |  CHEMBL562781 | C23H25N3O4 | 407.47 | 6 / 3 | 4.0 | Yes |
| 557933 |  CHEMBL253921 | C20H25N5O5S | 447.51 | 7 / 3 | 2.7 | Yes |
| 465652 |  CHEMBL3704566 | C20H21N3O6 | 399.403 | 8 / 3 | 1.5 | Yes |
| 557989 |  SCHEMBL13207001 | C19H23N5O4S | 417.484 | 7 / 3 | 2.5 | Yes |
| 558028 |  CHEMBL464509 | C20H23N5O2S | 397.497 | 7 / 3 | 4.6 | Yes |
| 536616 |  CHEMBL3956601 | C23H24ClN3O5S | 489.971 | 8 / 3 | 4.0 | Yes |
| 466068 |  CHEMBL3609001 | C20H19BFN3O3 | 379.198 | 6 / 3 | N/A | N/A |
| 28093 |  CHEMBL184583 | C18H17ClN2O2 | 328.796 | 4 / 0 | 4.4 | Yes |
| 31153 |  CHEMBL247356 | C25H31N3O5 | 453.539 | 7 / 3 | 4.7 | Yes |
| 467194 |  CHEMBL3609017 | C19H17BFN5O5 | 425.183 | 10 / 4 | N/A | N/A |
| 37912 |  CHEMBL220860 | C17H18ClN5O3S | 407.873 | 6 / 3 | 3.7 | Yes |
| 39950 |  CHEMBL496452 | C29H46O5 | 474.682 | 5 / 2 | 5.3 | No |
| 467911 |  CHEMBL3609014 | C24H21BFN5O3 | 457.272 | 8 / 3 | N/A | N/A |
| 42214 |  CHEMBL361312 | C20H21ClN2O2 | 356.85 | 4 / 0 | 4.7 | Yes |
| 43777 |  CHEMBL402952 | C26H24ClN3O5 | 493.944 | 7 / 3 | 5.0 | Yes |
| 558672 |  BDBM50227009 | C20H23N5O4S | 429.495 | 7 / 3 | 2.4 | Yes |
| 46568 |  CHEMBL387136 | C24H28BrClN6O5S | 627.939 | 9 / 5 | 3.5 | No |
| 468836 |  CHEMBL3704556 | C25H27N3O6 | 465.506 | 8 / 3 | 3.0 | Yes |
| 537215 |  SCHEMBL1198311 | C17H16Cl2FN3O4S | 448.29 | 6 / 4 | 3.0 | Yes |
| 537217 |  SCHEMBL1199471 | C17H16Cl2FN3O4S | 448.29 | 6 / 4 | 3.0 | Yes |
| 49779 |  CHEMBL218665 | C17H15BrF3N5O3S | 506.298 | 9 / 3 | 4.3 | No |
| 53054 |  1269775-42-9 | C24H34ClN7O3 | 504.032 | 7 / 3 | N/A | No |
| 54885 |  CHEMBL491506 | C21H21F2N3O5 | 433.412 | 9 / 3 | 3.2 | Yes |
| 55951 |  CHEMBL27446 | C14H9BrClN3O2 | 366.599 | 3 / 3 | 3.2 | Yes |
| 56539 |  diclofenac | C14H11Cl2NO2 | 296.147 | 3 / 2 | 4.4 | Yes |
| 56777 |  CHEMBL394899 | C24H29N3O5 | 439.512 | 7 / 3 | 4.4 | Yes |
| 57208 |  CHEMBL491487 | C22H24FN3O5 | 429.448 | 8 / 3 | 3.2 | Yes |
| 470233 |  CHEMBL3609002 | C19H17BFN3O3 | 365.171 | 6 / 4 | N/A | N/A |
| 59339 |  473728-58-4 | C23H27N3O5 | 425.485 | 7 / 3 | 3.8 | Yes |
| 62730 |  (R)-Ketoprofen | C16H14O3 | 254.285 | 3 / 1 | 3.1 | Yes |
| 62731 |  ketoprofen | C16H14O3 | 254.285 | 3 / 1 | 3.1 | Yes |
| 470815 |  CHEMBL3701184 | C24H27N3O6 | 453.495 | 8 / 3 | 2.8 | Yes |
| 470816 |  CHEMBL3609004 | C19H17BFN3O3 | 365.171 | 6 / 4 | N/A | N/A |
| 64591 |  CHEMBL218486 | C25H32BrClN6O4S | 627.983 | 8 / 4 | 6.1 | No |
| 66795 |  CHEMBL401512 | C22H22FN3O4 | 411.433 | 7 / 3 | 3.7 | Yes |
| 68396 |  CHEMBL253052 | C21H21F2N3O5 | 433.412 | 9 / 3 | 3.4 | Yes |
| 71874 |  CHEMBL246106 | C24H29N3O5 | 439.512 | 7 / 3 | 4.6 | Yes |
| 72801 |  CHEMBL283736 | C13H11N3O4 | 273.248 | 4 / 3 | 2.5 | Yes |
| 537816 |  SCHEMBL1197995 | C18H19ClFN3O4S | 427.875 | 6 / 4 | 2.8 | Yes |
| 559755 |  CHEMBL522959 | C23H27N5O4S | 469.56 | 9 / 3 | 5.3 | No |
| 559791 |  SCHEMBL13207006 | C21H27N5O4S | 445.538 | 7 / 3 | 3.3 | Yes |
| 80699 |  CHEMBL562950 | C20H20BrN3O4S | 478.361 | 7 / 3 | 4.0 | Yes |
| 537995 |  SCHEMBL1198537 | C21H23ClFN3O4S | 467.94 | 6 / 4 | 3.8 | Yes |
| 82393 |  CHEMBL183061 | C18H17ClN2O2 | 328.796 | 4 / 0 | 4.4 | Yes |
| 84210 |  CHEMBL246941 | C22H25N3O5 | 411.458 | 7 / 3 | 3.3 | Yes |
| 85933 |  CHEMBL183103 | C21H22ClN3O3 | 399.875 | 6 / 0 | 4.1 | Yes |
| 86009 |  CHEMBL2324200 | C20H10I4O4 | 821.914 | 4 / 2 | 6.4 | No |
| 87628 |  CHEMBL550945 | C21H23N3O4S | 413.492 | 7 / 3 | 3.7 | Yes |
| 88353 |  CHEMBL415446 | C21H23N3O4S | 413.492 | 7 / 3 | 3.7 | Yes |
| 560068 |  CID 136036526 | C21H24FN5O3S | 445.513 | 6 / 3 | 4.0 | Yes |
| 91999 |  CHEMBL472749 | C20H20FN3O5 | 401.394 | 8 / 3 | 2.6 | Yes |
| 92079 |  CHEMBL430116 | C19H20N4O5 | 384.392 | 8 / 3 | 2.0 | Yes |
| 474478 |  CHEMBL3701183 | C23H24FN3O6 | 457.458 | 9 / 3 | 2.3 | Yes |
| 94118 |  CHEMBL359670 | C13H11BrClN3O4S | 420.662 | 5 / 4 | 2.6 | Yes |
| 474560 |  CHEMBL3701192 | C25H27N3O7 | 481.505 | 9 / 3 | 2.1 | Yes |
| 560246 |  SCHEMBL13207037 | C21H27N5O4S | 445.538 | 7 / 3 | 3.3 | Yes |
| 96327 |  CHEMBL254516 | C26H24ClN3O5 | 493.944 | 7 / 3 | 5.0 | Yes |
| 100631 |  CHEMBL184882 | C22H25FN4O2 | 396.466 | 7 / 0 | 3.7 | Yes |
| 101645 |  CHEMBL246107 | C28H36N4O6 | 524.618 | 9 / 3 | 3.3 | No |
| 101723 |  CHEMBL393047 | C13H9BrClN3O3S | 402.647 | 4 / 3 | 2.7 | Yes |
| 105697 |  CHEMBL218744 | C23H29BrN6O4S | 565.487 | 8 / 4 | 4.7 | No |
| 108612 |  CHEMBL294095 | C14H13FN2O4S | 324.326 | 5 / 1 | 0.7 | Yes |
| 108653 |  CHEMBL404490 | C20H20ClN3O5 | 417.846 | 7 / 3 | 3.7 | Yes |
| 108655 |  CHEMBL253051 | C20H20ClN3O5 | 417.846 | 7 / 3 | 3.7 | Yes |
| 538706 |  CHEMBL3913959 | C22H24ClN3O6S2 | 526.019 | 10 / 3 | 3.7 | No |
| 534401 |  CHEMBL3915145 | C27H29N3O7S | 539.603 | 10 / 3 | 3.8 | No |
| 534403 |  CHEMBL3901913 | C27H29N3O7S | 539.603 | 10 / 3 | 3.8 | No |
| 112557 |  CHEMBL473959 | C19H16F3N3O5 | 423.348 | 10 / 3 | 2.9 | Yes |
| 113224 |  CHEMBL363840 | C28H36FN7O | 505.642 | 6 / 2 | 4.8 | No |
| 114524 |  CHEMBL252697 | C19H20N4O5 | 384.392 | 8 / 3 | 2.0 | Yes |
| 116673 |  CHEMBL561812 | C24H27N3O4 | 421.497 | 6 / 3 | 4.4 | Yes |
| 117424 |  CHEMBL245500 | C21H23N3O4S | 413.492 | 7 / 3 | 3.7 | Yes |
| 118609 |  CHEMBL185176 | C22H24N2O2 | 348.446 | 4 / 0 | 4.4 | Yes |
| 561019 |  CID 136036533 | C21H27N5O4S | 445.538 | 6 / 3 | 3.8 | Yes |
| 120564 |  CHEMBL253706 | C25H26N4O6 | 478.505 | 9 / 3 | 3.6 | Yes |
| 126754 |  CHEMBL184185 | C14H11BrClN3O3 | 384.614 | 3 / 4 | 2.9 | Yes |
| 478573 |  CHEMBL3704559 | C25H27N3O6 | 465.506 | 8 / 3 | 1.8 | Yes |
| 128299 |  CHEMBL523645 | C21H18F5N3O5 | 487.383 | 12 / 3 | 4.0 | No |
| 539251 |  CHEMBL3915853 | C24H27N3O5S | 469.556 | 8 / 3 | 3.6 | Yes |
| 129883 |  CHEMBL451438 | C33H52O8 | 576.771 | 8 / 2 | 5.1 | No |
| 135914 |  CHEMBL254370 | C22H23N3O4 | 393.443 | 6 / 3 | 3.6 | Yes |
| 561535 |  CHEMBL253702 | C21H25N5O5S | 459.521 | 7 / 3 | 2.5 | Yes |
| 138712 |  CHEMBL464301 | C21H18F3N3O4 | 433.387 | 9 / 3 | 3.8 | Yes |
| 480212 |  CHEMBL3609018 | C24H21BFN5O3 | 457.272 | 8 / 3 | N/A | N/A |
| 145128 |  CHEMBL425985 | C22H20ClN5O3S | 469.944 | 6 / 3 | 5.0 | Yes |
| 146178 |  CHEMBL523807 | C19H14Cl2F3N3O5 | 492.232 | 10 / 3 | 4.5 | Yes |
| 146450 |  CHEMBL363746 | C24H26F3N3O2 | 445.486 | 8 / 0 | 4.8 | Yes |
| 539733 |  CHEMBL3904195 | C25H27N3O7S | 513.565 | 10 / 3 | 3.3 | No |
| 146759 |  CHEMBL218115 | C20H21N3O5 | 383.404 | 7 / 3 | 2.7 | Yes |
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