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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL402952
Molecular formula	C26H24ClN3O5
IUPAC name	3-[[2-[1-[5-(2-chlorophenyl)furan-2-yl]propylamino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	493.944
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	5.0
Synonyms	SCHEMBL12262774 3-(2-(1-(5-(2-chlorophenyl)furan-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide BDBM50233591
Inchi Key	CJWSDDBPXOYIGG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H24ClN3O5/c1-4-17(20-13-12-19(35-20)14-8-5-6-10-16(14)27)28-21-22(25(33)24(21)32)29-18-11-7-9-15(23(18)31)26(34)30(2)3/h5-13,17,28-29,31H,4H2,1-3H3
PubChem CID	44446577
ChEMBL	CHEMBL402952
IUPHAR	N/A
BindingDB	50233591
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
43777	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
43776	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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