You can:
| Name | C-X-C chemokine receptor type 2 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | CXCR2 |
| Synonym | chemokine (C-X-C motif) receptor 2 KC receptor CD128 IL8RB IL-8R2 [ Show all ] |
| Disease | Cystic fibrosis; Chronic obstructive pulmonary disease Asthma Cancer Ischemia-reperfusion injury; Lung transplantation; Graft rejection in heart transplantation Fungal infections [ Show all ] |
| Length | 360 |
| Amino acid sequence | MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL |
| UniProt | P25025 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P25025 |
| 3D structure model | This predicted structure model is from GPCR-EXP P25025. |
| BioLiP | N/A |
| Therapeutic Target Database | T56923 |
| ChEMBL | CHEMBL2434 |
| IUPHAR | 69 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 2033 |  CHEMBL216602 | C20H21N3O5 | 383.404 | 7 / 3 | 2.6 | Yes |
| 463209 |  CHEMBL3658348 | C19H13F4N3O4S | 455.384 | 11 / 2 | 2.9 | No |
| 441844 |  CHEMBL3426944 | C20H15BF4N2O4S | 466.214 | 10 / 3 | N/A | N/A |
| 517334 |  CHEMBL3704558 | C25H25N3O7 | 479.489 | 9 / 3 | 2.8 | Yes |
| 517340 |  CHEMBL3704567 | C19H18ClN3O5 | 403.819 | 7 / 3 | 2.2 | Yes |
| 4273 |  CHEMBL57680 | C19H13FN2O6S | 416.379 | 7 / 2 | 1.4 | Yes |
| 459259 |  CHEMBL3658335 | C22H16BrFN2O3S | 487.343 | 6 / 1 | 4.7 | Yes |
| 533926 |  CHEMBL3976863 | C29H32FN3O6S | 569.648 | 10 / 2 | 4.6 | No |
| 459264 |  CHEMBL3658252 | C19H15FN8OS | 422.442 | 10 / 3 | 1.4 | Yes |
| 459267 |  CHEMBL3658272 | C20H14BrFN2O2S | 445.306 | 5 / 1 | 4.7 | Yes |
| 5875 |  diamide 7 | C22H22N2O3S | 394.489 | 4 / 3 | 4.8 | Yes |
| 6117 |  CHEMBL39835 | C14H11FN2O3S | 306.311 | 6 / 2 | 2.2 | Yes |
| 6366 |  methionine benzimidazole 6 | C23H25N3O3S | 423.531 | 5 / 2 | 4.8 | Yes |
| 459280 |  CHEMBL3426950 | C20H16BFN2O5S | 426.225 | 8 / 3 | N/A | N/A |
| 7509 |  CHEMBL207742 | C29H42N6O3 | 522.694 | 7 / 2 | 5.6 | No |
| 442009 |  CHEMBL3311396 | C14H11BrF2N2OS | 373.216 | 5 / 1 | 3.4 | Yes |
| 8169 |  CHEMBL254981 | C24H23F4N3O4 | 493.459 | 10 / 3 | 5.0 | Yes |
| 442044 |  CHEMBL3342293 | C20H14F4N2O2S | 422.398 | 8 / 1 | 5.3 | No |
| 8705 |  CHEMBL254572 | C23H21F4N3O4 | 479.432 | 10 / 3 | 4.6 | Yes |
| 9119 |  CHEMBL254569 | C19H17FN4O3S | 400.428 | 5 / 3 | 2.5 | Yes |
| 9354 |  CHEMBL244551 | C15H13F3N2O4S | 374.334 | 8 / 1 | 3.3 | Yes |
| 9719 |  SCHEMBL3928733 | C26H29NO5 | 435.52 | 5 / 2 | 5.6 | No |
| 9988 |  CHEMBL403313 | C21H21FN4O3S | 428.482 | 6 / 2 | 2.9 | Yes |
| 459314 |  CHEMBL3658347 | C18H14FN3O4S | 387.385 | 7 / 2 | 1.8 | Yes |
| 536266 |  SCHEMBL1198501 | C18H16ClF2N3O6S | 475.848 | 9 / 4 | 2.9 | Yes |
| 12654 |  CHEMBL220182 | C23H23N3O6 | 437.452 | 8 / 3 | 3.4 | Yes |
| 12680 |  CHEMBL26830 | C14H9BrClN3O2 | 366.599 | 3 / 3 | 3.7 | Yes |
| 442175 |  CHEMBL3342292 | C19H14FN3O3S | 383.397 | 6 / 1 | 4.0 | Yes |
| 13277 |  CHEMBL430376 | C13H10ClN3O4 | 307.69 | 4 / 3 | 2.6 | Yes |
| 442184 |  CHEMBL3342301 | C23H18FN3OS | 403.475 | 4 / 1 | 4.5 | Yes |
| 13444 |  CHEMBL404661 | C18H17BrFN3O3S | 454.314 | 4 / 3 | 3.5 | Yes |
| 13457 |  CHEMBL250689 | C28H36FN3O2 | 465.613 | 4 / 2 | 5.2 | No |
| 464522 |  CHEMBL3609011 | C19H18BFN4O3 | 380.186 | 7 / 3 | N/A | N/A |
| 521860 |  CHEMBL3819542 | C18H19Cl3N4O4S | 493.784 | 6 / 3 | 3.5 | Yes |
| 442193 |  478261-70-0 | C18H11Cl2N3OS | 388.266 | 4 / 1 | 4.5 | Yes |
| 459346 |  CHEMBL3658279 | C20H13F3N2O2S | 402.391 | 7 / 1 | 4.2 | Yes |
| 15090 |  disulfiram | C10H20N2S4 | 296.524 | 4 / 0 | 3.9 | Yes |
| 521941 |  AM-0902 | C17H15ClN6O2 | 370.797 | 6 / 0 | 2.3 | Yes |
| 459355 |  CHEMBL3658338 | C19H16BFN2O4S | 398.215 | 7 / 4 | N/A | N/A |
| 536413 |  SCHEMBL1199104 | C17H18Cl2N4O4S | 445.315 | 6 / 4 | 2.6 | Yes |
| 16836 |  CHEMBL562781 | C23H25N3O4 | 407.47 | 6 / 3 | 4.0 | Yes |
| 442340 |  CHEMBL3342311 | C20H15FN2O3S | 382.409 | 6 / 2 | 3.7 | Yes |
| 442358 |  CHEMBL3342298 | C22H17FN4OS | 404.463 | 5 / 1 | 4.1 | Yes |
| 18116 |  CHEMBL388685 | C10H10F3NO5S | 313.247 | 8 / 2 | 2.0 | Yes |
| 19077 |  CHEMBL564068 | C23H23N3O4 | 405.454 | 6 / 4 | 4.0 | Yes |
| 19238 |  CHEMBL2349332 | C18H21BrFN5OS2 | 486.422 | 9 / 3 | 5.2 | No |
| 536473 |  CHEMBL3956663 | C24H27N3O7 | 469.494 | 9 / 3 | 2.5 | Yes |
| 459387 |  CHEMBL3658300 | C18H13FN2O3S | 356.371 | 6 / 1 | 3.4 | Yes |
| 19792 |  CHEMBL202396 | C18H13ClN4OS2 | 400.899 | 7 / 1 | 5.5 | No |
| 459394 |  CHEMBL3658263 | C20H14FN3OS2 | 395.47 | 6 / 1 | 4.6 | Yes |
| 459400 |  CHEMBL3658331 | C25H17F4N3O2S2 | 531.544 | 10 / 1 | 6.4 | No |
| 20908 |  CHEMBL397237 | C15H15F2N5OS2 | 383.436 | 10 / 3 | 3.3 | Yes |
| 20910 |  CHEMBL414894 | C15H15F2N5OS2 | 383.436 | 10 / 3 | 3.3 | Yes |
| 20924 |  CHEMBL61655 | C15H15FN2O4S | 338.353 | 5 / 1 | 1.2 | Yes |
| 557934 |  CHEMBL253921 | C20H25N5O5S | 447.51 | 7 / 3 | 2.7 | Yes |
| 522115 |  CHEMBL3775436 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 522196 |  CHEMBL3775769 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 517443 |  CHEMBL3704566 | C20H21N3O6 | 399.403 | 8 / 3 | 1.5 | Yes |
| 459408 |  CHEMBL3658285 | C20H14FN3O4S | 411.407 | 7 / 1 | 3.9 | Yes |
| 22938 |  CHEMBL314335 | C17H16N4O | 292.342 | 3 / 1 | 2.8 | Yes |
| 557990 |  SCHEMBL13207001 | C19H23N5O4S | 417.484 | 7 / 3 | 2.5 | Yes |
| 23507 |  CHEMBL379438 | C16H11N3O5 | 325.28 | 7 / 3 | 2.5 | Yes |
| 558027 |  CHEMBL464509 | C20H23N5O2S | 397.497 | 7 / 3 | 4.6 | Yes |
| 536615 |  CHEMBL3956601 | C23H24ClN3O5S | 489.971 | 8 / 3 | 4.0 | Yes |
| 25139 |  SCHEMBL842188 | C14H18N6OS3 | 382.519 | 10 / 3 | 2.7 | Yes |
| 25145 |  CHEMBL271703 | C16H16F2N6OS | 378.402 | 10 / 3 | 2.1 | Yes |
| 522333 |  CXCR2-IN-1 | C19H20Cl2FN3O4S | 476.344 | 6 / 3 | 3.9 | Yes |
| 466067 |  CHEMBL3609001 | C20H19BFN3O3 | 379.198 | 6 / 3 | N/A | N/A |
| 459440 |  CHEMBL3658294 | C22H13F7N2O2S | 502.407 | 11 / 1 | 5.8 | No |
| 26011 |  CHEMBL2349182 | C19H25N5OS2 | 403.563 | 8 / 3 | 4.8 | Yes |
| 522370 |  CHEMBL3819221 | C19H18Cl2FN3O3 | 426.269 | 4 / 3 | 4.3 | Yes |
| 27202 |  CHEMBL2203713 | C18H22N4S | 326.462 | 4 / 2 | 2.9 | Yes |
| 27454 |  CHEMBL86276 | C15H14N4 | 250.305 | 3 / 1 | 2.9 | Yes |
| 29021 |  CHEMBL2024082 | C13H14F3NO6S2 | 401.371 | 9 / 1 | 2.6 | Yes |
| 29552 |  CHEMBL213130 | C19H23N3O4 | 357.41 | 6 / 3 | 3.0 | Yes |
| 29672 |  CHEMBL254176 | C24H24N4O4 | 432.48 | 7 / 3 | 3.7 | Yes |
| 442828 |  CHEMBL3342316 | C20H17BN6O3S | 432.265 | 8 / 4 | N/A | N/A |
| 442850 |  CHEMBL3342317 | C18H16BN3O3S | 365.214 | 6 / 3 | N/A | N/A |
| 30458 |  CHEMBL404918 | C23H23F2N3O4 | 443.451 | 8 / 3 | 4.2 | Yes |
| 30677 |  SCHEMBL3928229 | C29H24F3NO4 | 507.509 | 7 / 2 | 6.8 | No |
| 30830 |  CHEMBL377120 | C24H37N5O2 | 427.593 | 6 / 2 | 4.5 | Yes |
| 442874 |  CHEMBL3342279 | C18H19FN2O2S | 346.42 | 5 / 1 | 3.2 | Yes |
| 536790 |  CHEMBL3889627 | C23H27N5O3S | 453.561 | 5 / 2 | 2.6 | Yes |
| 31152 |  CHEMBL247356 | C25H31N3O5 | 453.539 | 7 / 3 | 4.7 | Yes |
| 459494 |  CHEMBL3658345 | C18H14FN3O3S | 371.386 | 6 / 1 | 2.1 | Yes |
| 459501 |  CHEMBL3658280 | C28H31FN2O3S | 494.625 | 6 / 2 | 7.0 | No |
| 459511 |  SCHEMBL6927997 | C18H14FN3O2 | 323.327 | 5 / 1 | 2.8 | Yes |
| 33479 |  UNII-7W7511NPF8 | C20H20N2O3S | 368.451 | 6 / 1 | 1.8 | Yes |
| 34109 |  CHEMBL309253 | C15H11Cl2N3S | 336.234 | 1 / 1 | 4.4 | Yes |
| 467193 |  CHEMBL3609017 | C19H17BFN5O5 | 425.183 | 10 / 4 | N/A | N/A |
| 443088 |  CHEMBL3354830 | C18H19ClN4O4S | 422.884 | 5 / 3 | 1.9 | Yes |
| 443130 |  CHEMBL3342302 | C20H16F2N2OS | 370.418 | 5 / 1 | 4.6 | Yes |
| 459546 |  CHEMBL3658257 | C19H13FN4OS2 | 396.458 | 7 / 1 | 4.0 | Yes |
| 37129 |  CHEMBL314498 | C15H13N3O | 251.289 | 2 / 1 | 2.5 | Yes |
| 37911 |  CHEMBL220860 | C17H18ClN5O3S | 407.873 | 6 / 3 | 3.7 | Yes |
| 37977 |  CHEMBL233973 | C15H12ClN3O4S | 365.788 | 5 / 3 | 2.3 | Yes |
| 38044 |  39696-48-5 | C9H9N3S | 191.252 | 1 / 1 | 1.6 | Yes |
| 38853 |  CHEMBL402942 | C22H23FN4O4S | 458.508 | 7 / 3 | 2.5 | Yes |
| 443297 |  CHEMBL3355244 | C17H18ClF2N3O4S | 433.855 | 7 / 3 | 2.7 | Yes |
| 467912 |  CHEMBL3609014 | C24H21BFN5O3 | 457.272 | 8 / 3 | N/A | N/A |
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