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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL253921
Molecular formula	C20H25N5O5S
IUPAC name	3-[[4-[(1R)-1-(furan-2-yl)-2,2-dimethylpropyl]imino-1,1-dioxo-1,2,5-thiadiazol-3-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	447.51
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	2.7
Synonyms	BDBM50227006 SCHEMBL13405687 3-[4-((R)-1-furan-2-yl-2,2-dimethyl-propylamino)-1,1-dioxo-1H-1lambda6-[1,2,5]thiadiazol-3-ylamino]-2-hydroxy-N,N-dimethyl-benzamide
Inchi Key	BDLSEEFGQREQHH-INIZCTEOSA-N
Inchi ID	InChI=1S/C20H25N5O5S/c1-20(2,3)16(14-10-7-11-30-14)22-18-17(23-31(28,29)24-18)21-13-9-6-8-12(15(13)26)19(27)25(4)5/h6-11,16,26H,1-5H3,(H,21,23)(H,22,24)/t16-/m0/s1
PubChem CID	135539055
ChEMBL	CHEMBL253921
IUPHAR	N/A
BindingDB	50227006
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557933	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
557934	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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