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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL247356
Molecular formula	C25H31N3O5
IUPAC name	3-[[2-[[(1R)-2,2-dimethyl-1-(4-propan-2-ylfuran-2-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	453.539
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	4.7
Synonyms	BDBM50211448 SCHEMBL12262841 (R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)-2,2-dimethylpropylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide
Inchi Key	BRNMYMQVVHGBOR-QHCPKHFHSA-N
Inchi ID	InChI=1S/C25H31N3O5/c1-13(2)14-11-17(33-12-14)23(25(3,4)5)27-19-18(21(30)22(19)31)26-16-10-8-9-15(20(16)29)24(32)28(6)7/h8-13,23,26-27,29H,1-7H3/t23-/m0/s1
PubChem CID	44440873
ChEMBL	CHEMBL247356
IUPHAR	N/A
BindingDB	50211448
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
31153	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
31152	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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