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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3704567
Molecular formula	C19H18ClN3O5
IUPAC name	3-[(6-chloro-2-oxo-1H-pyridin-3-yl)amino]-4-[[(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino]cyclobut-3-ene-1,2-dione
Molecular weight	403.819
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	2.2
Synonyms	3-(6-chloro-2-hydroxypyridin-3-ylamino)-4-{[(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino}cyclobut-3-ene-1,2-dione AFJOTRXLUOFBJR-UHFFFAOYSA-N SCHEMBL14895009
Inchi Key	AFJOTRXLUOFBJR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H18ClN3O5/c1-9-3-5-11(28-9)17(19(2)7-27-8-19)23-14-13(15(24)16(14)25)21-10-4-6-12(20)22-18(10)26/h3-6,17,21,23H,7-8H2,1-2H3,(H,22,26)
PubChem CID	71525701
ChEMBL	CHEMBL3704567
IUPHAR	N/A
BindingDB	172360
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463403	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
517340	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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