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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL220182
Molecular formula	C23H23N3O6
IUPAC name	3-[[2-[[(1R)-1-(1,3-benzodioxol-5-yl)propyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	437.452
Hydrogen bond acceptor	8
Hydrogen bond donor	3
XlogP	3.4
Synonyms	BDBM50200875 SCHEMBL12086710 (R)-3-(2-(1-(benzo[d][1,3]dioxol-5-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Inchi Key	ARPPAIXHGDGLEQ-CQSZACIVSA-N
Inchi ID	InChI=1S/C23H23N3O6/c1-4-14(12-8-9-16-17(10-12)32-11-31-16)24-18-19(22(29)21(18)28)25-15-7-5-6-13(20(15)27)23(30)26(2)3/h5-10,14,24-25,27H,4,11H2,1-3H3/t14-/m1/s1
PubChem CID	16098480
ChEMBL	CHEMBL220182
IUPHAR	N/A
BindingDB	50200875
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12655	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
12654	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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