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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2349332
Molecular formula	C18H21BrFN5OS2
IUPAC name	(2R)-2-[[2-amino-5-[(4-bromo-2-fluorophenyl)methylsulfanyl]-[1,3]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methylpentan-1-ol
Molecular weight	486.422
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	5.2
Synonyms	BDBM50432429 SCHEMBL5232446
Inchi Key	BAWCTQVXGNPSAG-GFCCVEGCSA-N
Inchi ID	InChI=1S/C18H21BrFN5OS2/c1-9(2)5-12(7-26)22-15-14-16(23-17(21)28-14)25-18(24-15)27-8-10-3-4-11(19)6-13(10)20/h3-4,6,9,12,26H,5,7-8H2,1-2H3,(H3,21,22,23,24,25)/t12-/m1/s1
PubChem CID	21035680
ChEMBL	CHEMBL2349332
IUPHAR	N/A
BindingDB	50432429
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19238	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360
19237	CX3C chemokine receptor 1	P49238	CX3CR1	Homo sapiens (Human)	355

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