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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL425985
Molecular formula	C22H20ClN5O3S
IUPAC name	1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-3-cyano-2-(2-phenylphenyl)guanidine
Molecular weight	469.944
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	5.0
Synonyms	BDBM50193977 1-[4-chloro-3-(dimethylsulfamoyl)-2-hydroxyphenyl]-2-cyano-3-(2-phenylphenyl)guanidine
Inchi Key	IYZWLQHDOCJREA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H20ClN5O3S/c1-28(2)32(30,31)21-17(23)12-13-19(20(21)29)27-22(25-14-24)26-18-11-7-6-10-16(18)15-8-4-3-5-9-15/h3-13,29H,1-2H3,(H2,25,26,27)
PubChem CID	44419449
ChEMBL	CHEMBL425985
IUPHAR	N/A
BindingDB	50193977
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
145128	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
145127	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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