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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1198537
Molecular formula	C21H23ClFN3O4S
IUPAC name	1-[3-[[(1R,5S)-8-azabicyclo[3.2.1]octan-3-yl]sulfonyl]-4-chloro-2-hydroxyphenyl]-3-(3-fluoro-2-methylphenyl)urea
Molecular weight	467.94
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	3.8
Synonyms	SCHEMBL1198986 CHEMBL3952903 SCHEMBL12878816
Inchi Key	FLPRVHAJERWVDF-PBWFPOADSA-N
Inchi ID	InChI=1S/C21H23ClFN3O4S/c1-11-16(23)3-2-4-17(11)25-21(28)26-18-8-7-15(22)20(19(18)27)31(29,30)14-9-12-5-6-13(10-14)24-12/h2-4,7-8,12-14,24,27H,5-6,9-10H2,1H3,(H2,25,26,28)/t12-,13+,14?
PubChem CID	57649026
ChEMBL	CHEMBL3952903
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
537995	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
537994	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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