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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BDBM50227009
Molecular formula	C20H23N5O4S
IUPAC name	3-[[4-[[(R)-furan-2-yl-(1-methylcyclopropyl)methyl]amino]-1-oxo-1,2,5-thiadiazol-3-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	429.495
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	2.4
Synonyms	3-(4-{[(R)-furan-2-yl-(1-methyl-cyclopropyl)-methyl]-amino}-1-oxo-1H-1lambda4-[1,2,5]thiadiazol-3-ylamino)-2-hydroxy-N,N-dimethyl-benzamide
Inchi Key	CMANXHXTSWTYRG-XSTXYMSBSA-N
Inchi ID	InChI=1S/C20H23N5O4S/c1-20(9-10-20)16(14-8-5-11-29-14)22-18-17(23-30(28)24-18)21-13-7-4-6-12(15(13)26)19(27)25(2)3/h4-8,11,16,26H,9-10H2,1-3H3,(H,21,23)(H,22,24)/t16-,30?/m0/s1
PubChem CID	136104502
ChEMBL	CHEMBL252911
IUPHAR	N/A
BindingDB	50227009
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558672	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
558673	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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