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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3701192
Molecular formula	C25H27N3O7
IUPAC name	3-[2-hydroxy-3-(morpholine-4-carbonyl)anilino]-4-[[(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino]cyclobut-3-ene-1,2-dione
Molecular weight	481.505
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	2.1
Synonyms	SCHEMBL14894651 3-[2-Hydroxy-3-(morpholine-4-carbonyl)phenylamino]-4-{[(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino}cyclobut-3-ene-1,2-dione GENDPWSLDZSRJG-UHFFFAOYSA-N
Inchi Key	GENDPWSLDZSRJG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H27N3O7/c1-14-6-7-17(35-14)23(25(2)12-34-13-25)27-19-18(21(30)22(19)31)26-16-5-3-4-15(20(16)29)24(32)28-8-10-33-11-9-28/h3-7,23,26-27,29H,8-13H2,1-2H3
PubChem CID	71525345
ChEMBL	CHEMBL3701192
IUPHAR	N/A
BindingDB	172335
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
474560	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
517820	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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