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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL218665
Molecular formula	C17H15BrF3N5O3S
IUPAC name	2-(2-bromophenyl)-1-cyano-3-[3-(dimethylsulfamoyl)-2-hydroxy-4-(trifluoromethyl)phenyl]guanidine
Molecular weight	506.298
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	4.3
Synonyms	BDBM50193971 3-{[[(2-bromophenyl)amino](cyanoimino)methyl]amino}-2-hydroxy-N,N-dimethyl-6-(trifluoromethyl)benzenesulfonamide
Inchi Key	CSVHKWZKMWYMAX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H15BrF3N5O3S/c1-26(2)30(28,29)15-10(17(19,20)21)7-8-13(14(15)27)25-16(23-9-22)24-12-6-4-3-5-11(12)18/h3-8,27H,1-2H3,(H2,23,24,25)
PubChem CID	44419482
ChEMBL	CHEMBL218665
IUPHAR	N/A
BindingDB	50193971
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
49779	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
49778	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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