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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3913959
Molecular formula	C22H24ClN3O6S2
IUPAC name	6-chloro-2-hydroxy-N,N-dimethyl-3-[[2-[[(5-methylfuran-2-yl)-(thiolan-2-yl)methyl]amino]-3,4-dioxocyclobuten-1-yl]amino]benzenesulfonamide
Molecular weight	526.019
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	3.7
Synonyms	6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)-(tetrahydrothiophen-2-yl)methyl]amino}-3,4-dioxocyclobut-1-enylamino)benzenesulfonamide HCGUUQDQSYMJAU-UHFFFAOYSA-N (+)-6-chloro-2-hydroxy-N,N-dimethyl-3-(2-{[(5-methylfuran-2-yl)-(tetrahydrothiophen-2-yl)methyl]amino}-3,4-dioxocyclobut-1-enylamino)benzenesulfonamide SCHEMBL14894987
Inchi Key	HCGUUQDQSYMJAU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24ClN3O6S2/c1-11-6-9-14(32-11)16(15-5-4-10-33-15)25-18-17(20(28)21(18)29)24-13-8-7-12(23)22(19(13)27)34(30,31)26(2)3/h6-9,15-16,24-25,27H,4-5,10H2,1-3H3
PubChem CID	71526159
ChEMBL	CHEMBL3913959
IUPHAR	N/A
BindingDB	236813
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
538706	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
538705	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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