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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL253706
Molecular formula	C25H26N4O6
IUPAC name	3-[[2-[1-[4-(3,5-dimethyl-1,2-oxazol-4-yl)furan-2-yl]propylamino]-3,4-dioxocyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	478.505
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	3.6
Synonyms	BDBM50233590 SCHEMBL12262843 3-(2-(1-(4-(3,5-dimethylisoxazol-4-yl)furan-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Inchi Key	HPCHAHFHNCQQJC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H26N4O6/c1-6-16(18-10-14(11-34-18)19-12(2)28-35-13(19)3)26-20-21(24(32)23(20)31)27-17-9-7-8-15(22(17)30)25(33)29(4)5/h7-11,16,26-27,30H,6H2,1-5H3
PubChem CID	44446604
ChEMBL	CHEMBL253706
IUPHAR	N/A
BindingDB	50233590
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
120564	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
120563	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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