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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	diclofenac
Molecular formula	C14H11Cl2NO2
IUPAC name	2-[2-(2,6-dichloroanilino)phenyl]acetic acid
Molecular weight	296.147
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.4
Synonyms	KBioGR_002306 CGP-45840B Olfen MCULE-1824024270 D0TG1H ProSorb-D Novo-Difenac Diclo-Puren Solaraze T Diclofenac [USAN:INN:BAN] SR-01000003041-3 2-(2-((2,6-Dichlorophenyl)amino)phenyl)acetic acid Diclord Voltaren 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID Duravolten ZINC1281 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid F0722-0745 [o-(2,6-dichloro-anilino)-phenyl]-acetic acid ACMC-209d8r HY-15036 BCP09087 KBio2_002306 BPBio1_000516 KS-000001OB CHEMBL139 Prestwick0_000594 NCGC00021125-01 DB00586 SC-16284 o-(2,6-dichloroanilino)phenylacetic acid Diclofenac (sodium matrix patch, pain) Spectrum2_000991 144O8QL0L1 Diclofenacum STK984493 2-[(2,6-dichlorophenyl)-amino]-phenyl-acetic acid DIF Voltaren SR 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid EC 239-348-5 Zorvolex (TN) AB01275502_02 GP-45840 AKOS001579542 IDI1_000402 Benfofen KBio2_006546 BRN 2146636 C01690 LS-11575 CTK8B0851 Prestwick3_000594 NINDS_000402 Dichlofenal Solaraze Diclofenac resinate Spectrum5_000867 2-((2,6-Dichlorophenyl)amino)benzeneacetic acid Diclonate P UNM000001216103 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid Dolobasan Xenid 2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetic acid EINECS 239-348-5 [2-(2,6-Dichloroanilino)phenyl]acetic acid AC1L1F0T HMS501E04 Assaren KBio1_000402 Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]- KBio3_002786 KBioSS_001410 CHEBI:47381 Oprea1_011155 MLS006011795 D30801 Rhumalgan Novo-Difenac SR Diclobenin SPBio_001081 056D694 Diclofenaco SR-38 2-(2-(2,6-dichlorophenylamino)phenyl)acetic acid Dicloreum Voltaren Ophtha 2-[2-(2,6-dichloroanilino)phenyl]acetic acid Dyloject Zorovolex 2b17 FT-0624731 {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid AJ-07992 I14-7739 BCP13860 KBio2_003978 BRD-K08252256-236-05-6 BSPBio_000468 KS-1258 cMAP_000014 Prestwick1_000594 NCGC00021125-02 DCOPUUMXTXDBNB-UHFFFAOYSA-N SCHEMBL2799 Diclofenac (USAN/INN) Spectrum3_000385 15307-81-0 (mono-potassium salt) Diclofenacum [INN-Latin] TC-110178 2-[(2,6-dichlorophenyl)amino]-benzeneacetic acid DivK1c_000272 Voltaren-XR 2-[2-(2,6-dichlorophenylamino)-phenyl]-acetic acid Ecofenac [2-(2,6-dichloro-phenylamino)-phenyl]-acetic acid AB1009343 GTPL2714 ANW-21433 ISV-205 Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)- KBio2_007442 Cataflam M-7482 D07816 Primofenac Novapirina Diclo-Phlogont Solaraze (TN) Diclofenac [INN:BAN] Spectrum_000930 2-(2,6-Dichloroanilino)phenylacetic Acid Diclophenac Voldal 2-[(2,6-dichlorophenyl)amino]phenylacetic acid DTXSID6022923 Z57664869 2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetic Acid (Diclofenac) Epitope ID:116873 [2-(2,6-Dichloroanilino)phenyl]acetic acid # ACETIC ACID, (o-(2,6-DICHLOROANILINO)PHENYL)- HSDB 7234 BC208012 KBio2_001410 BIDD:GT0380 KBioGR_001051 KBioSS_002308 Pennsaid MolPort-000-003-072 D3748 SBI-0051341.P003 Nu-Diclo SPBio_002687 Diclofenaco [INN-Spanish] ST51039044 2-[(2,6-dichlorophenyl)-amino]-benzeneacetic acid Dicrofenac Voltaren Rapide 2-[2-(2,6-dichloroanilino)phenyl]acetic acid. EBD50236 Zorvolex AB01275502-01 GP-45,840 AK-75694 IDI1_000272 BDBM13066 KBio2_004874 BRD-K08252256-236-17-1 BSPBio_002169 Lopac0_000441 CS-2862 Prestwick2_000594 NINDS_000272 dichlofenac SMR001550371 Diclofenac acid Spectrum4_000506 15307-86-5 Diclofenamic acid UNII-144O8QL0L1 2-[(2,6-dichlorophenyl)amino]-phenyl-acetic acid DivK1c_000402 Voltarol 2-[2-(2,6-dichlorophenylamino)phenyl]-acetic acid Effekton [2-(2,6-Dichloroanilino)phenyl]-acetic acid; 2-[2-(2,6-Dichlorophenyl)aminophenyl]ethanoic acid AC-27673 HMS2090C10 Apo-Diclo KBio1_000272 Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)- (9CI) KBio3_001389 [ Show all ]
Inchi Key	DCOPUUMXTXDBNB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
PubChem CID	3033
ChEMBL	CHEMBL139
IUPHAR	N/A
BindingDB	13066
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
56539	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350

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