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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL473959
Molecular formula	C19H16F3N3O5
IUPAC name	3-[[3,4-dioxo-2-[[(1S)-2,2,2-trifluoro-1-(furan-2-yl)ethyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	423.348
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	2.9
Synonyms	BDBM50248279 SCHEMBL12262977 (S)-3-(3,4-dioxo-2-(2,2,2-trifluoro-1-(furan-2-yl)ethylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide
Inchi Key	HEBGAKBUHZNNIN-KRWDZBQOSA-N
Inchi ID	InChI=1S/C19H16F3N3O5/c1-25(2)18(29)9-5-3-6-10(14(9)26)23-12-13(16(28)15(12)27)24-17(19(20,21)22)11-7-4-8-30-11/h3-8,17,23-24,26H,1-2H3/t17-/m0/s1
PubChem CID	42642630
ChEMBL	CHEMBL473959
IUPHAR	N/A
BindingDB	50248279
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
112557	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
112556	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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