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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL246941
Molecular formula	C22H25N3O5
IUPAC name	3-[[3,4-dioxo-2-[[(1R)-1-(4-propan-2-ylfuran-2-yl)ethyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	411.458
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	3.3
Synonyms	SCHEMBL12087245 (R)-2-hydroxy-3-(2-(1-(4-isopropylfuran-2-yl)ethylamino)-3,4-dioxocyclobut-1-enylamino)-N,N-dimethylbenzamide BDBM50211456
Inchi Key	FPOWMMYKRZVTRO-GFCCVEGCSA-N
Inchi ID	InChI=1S/C22H25N3O5/c1-11(2)13-9-16(30-10-13)12(3)23-17-18(21(28)20(17)27)24-15-8-6-7-14(19(15)26)22(29)25(4)5/h6-12,23-24,26H,1-5H3/t12-/m1/s1
PubChem CID	9978981
ChEMBL	CHEMBL246941
IUPHAR	N/A
BindingDB	50211456
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
84210	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
84209	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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