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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL254370
Molecular formula	C22H23N3O4
IUPAC name	3-[[3,4-dioxo-2-[[(1R)-1-phenylpropyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N-dimethylbenzamide
Molecular weight	393.443
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	3.6
Synonyms	SCHEMBL247103 (R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide BDBM50236053
Inchi Key	ILEJORXRDPNPIM-OAHLLOKOSA-N
Inchi ID	InChI=1S/C22H23N3O4/c1-4-15(13-9-6-5-7-10-13)23-17-18(21(28)20(17)27)24-16-12-8-11-14(19(16)26)22(29)25(2)3/h5-12,15,23-24,26H,4H2,1-3H3/t15-/m1/s1
PubChem CID	10200589
ChEMBL	CHEMBL254370
IUPHAR	N/A
BindingDB	50236053
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
135914	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
135915	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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